INT112179

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Context Info
Confidence 0.30
First Reported 2003
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 5
Disease Relevance 1.17
Pain Relevance 3.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CRCP) nucleus (CRCP) response to stress (CRCP)
Anatomy Link Frequency
DRG 3
dorsal horn 2
spinal 1
CRCP (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 42 99.68 Very High Very High Very High
Dorsal horn 6 99.68 Very High Very High Very High
antagonist 3 99.58 Very High Very High Very High
Inflammation 9 99.38 Very High Very High Very High
spinal dorsal horn 3 99.08 Very High Very High Very High
intrathecal 3 99.02 Very High Very High Very High
Sciatic nerve 3 98.56 Very High Very High Very High
Pain 6 96.20 Very High Very High Very High
Dorsal horn neuron 3 94.12 High High
medulla 3 82.40 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 6 99.38 Very High Very High Very High
Pain 3 96.20 Very High Very High Very High
Urological Neuroanatomy 3 75.84 Quite High
Fatigue 2 69.00 Quite High
Sleep Disorders 12 64.88 Quite High
Skin Ulcer 20 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Nicotine Addiction 2 5.00 Very Low Very Low Very Low
Emergencies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Carrageenan-induced plantar inflammation produced a dramatic bilateral increase in RCP expression in the dorsal horn while a partial sciatic nerve ligation reduced RCP expression in the ipsilateral superficial dorsal horn.
Spec (partial) Positive_regulation (increase) of Gene_expression (expression) of RCP in dorsal horn associated with inflammation, dorsal horn and sciatic nerve
1) Confidence 0.30 Published 2003 Journal Neuroscience Section Abstract Doc Link 12895509 Disease Relevance 0.26 Pain Relevance 1.32
The intrathecal injection of the antagonist CGRP(8-37) markedly increased RCP expression in the lumbar DRG and spinal dorsal horn.
Positive_regulation (increased) of Gene_expression (expression) of RCP in DRG associated with spinal dorsal horn, antagonist, calcitonin gene-related peptide and intrathecal
2) Confidence 0.30 Published 2003 Journal Neuroscience Section Abstract Doc Link 12895509 Disease Relevance 0.27 Pain Relevance 1.20
The intervention rota was based on the schedule that the RCP proposed as the most promising in its review in minimizing the risk to patient safety and doctorsÂ’ health with particular regard to the length and frequency of night shifts.12
Positive_regulation (review) of Gene_expression (proposed) of RCP
3) Confidence 0.12 Published 2009 Journal QJM: An International Journal of Medicine Section Body Doc Link PMC2659599 Disease Relevance 0.19 Pain Relevance 0
The intervention rota was based on the schedule that the RCP proposed as the most promising in its review in minimizing the risk to patient safety and doctorsÂ’ health with particular regard to the length and frequency of night shifts.12
Positive_regulation (promising) of Gene_expression (proposed) of RCP
4) Confidence 0.12 Published 2009 Journal QJM: An International Journal of Medicine Section Body Doc Link PMC2659599 Disease Relevance 0.19 Pain Relevance 0
The intrathecal injection of the antagonist CGRP(8-37) markedly increased RCP expression in the lumbar DRG and spinal dorsal horn.
Positive_regulation (increased) of in spinal Gene_expression (expression) of RCP in DRG associated with spinal dorsal horn, antagonist, calcitonin gene-related peptide and intrathecal
5) Confidence 0.10 Published 2003 Journal Neuroscience Section Abstract Doc Link 12895509 Disease Relevance 0.27 Pain Relevance 1.20

General Comments

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