INT112204

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Context Info
Confidence 0.32
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Pck1) nucleolus (Pck1) nucleus (Pck1)
lipid metabolic process (Pck1) cytoplasm (Pck1)
Pck1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 1 92.28 High High
Opioid 3 84.84 Quite High
antagonist 1 82.24 Quite High
nav1.8 1 75.00 Quite High
Serotonin 1 54.08 Quite High
tetrodotoxin 1 48.80 Quite Low
narcan 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 9 98.64 Very High Very High Very High
Targeted Disruption 1 85.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduction of the mRNA or protein levels of hepatic PEPCK was also impeded in the same group of STZ-induced diabetic rats.
Negative_regulation (impeded) of Negative_regulation (Reduction) of PEPCK associated with diabetes mellitus
1) Confidence 0.32 Published 2006 Journal Diabetes Section Abstract Doc Link 16505249 Disease Relevance 0.76 Pain Relevance 0.33
While the effect of GTP(gammaS) was prevented by pretreatment with H7 (100 micro M), a non-selective PKA/PKC inhibitor, the fluoride-induced increase in Na(v)1.8 current was not sensitive to H7 (100 micro M), or to inclusion of deferoxamine (1 mM) in the intracellular solution.
Negative_regulation (prevented) of Negative_regulation (effect) of GTP
2) Confidence 0.05 Published 2003 Journal Exp Brain Res Section Abstract Doc Link 12898089 Disease Relevance 0 Pain Relevance 0.10

General Comments

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