INT112233

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.44
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NDC80) mitosis (NDC80) chromosome segregation (NDC80)
chromosome (NDC80) nucleus (NDC80) cell cycle (NDC80)
Anatomy Link Frequency
capillary 1
NDC80 (Homo sapiens)
Pain Link Frequency Relevance Heat
tramadol 1 99.50 Very High Very High Very High
fluoxetine 1 98.96 Very High Very High Very High
methadone 1 98.72 Very High Very High Very High
antagonist 32 88.00 High High
medulla 4 49.56 Quite Low
headache 4 49.44 Quite Low
trigger zone 8 47.96 Quite Low
Serotonin 4 32.04 Quite Low
Dopamine 2 26.88 Quite Low
Neurotransmitter 4 25.28 Quite Low
Disease Link Frequency Relevance Heat
Vomiting 254 99.98 Very High Very High Very High
Rheumatoid Arthritis 18 88.00 High High
Headache 4 49.44 Quite Low
Constipation 4 48.40 Quite Low
Cancer 4 16.72 Low Low
Adverse Drug Reaction 6 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was first approved by the FDA in 2003 and is currently licensed in the USA for the prevention of acute nausea and vomiting associated with MEC and HEC, and the prevention of delayed nausea and vomiting associated with MEC.
HEC Binding (associated) of associated with vomiting
1) Confidence 0.01 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2387285 Disease Relevance 1.29 Pain Relevance 0.16
Four chiral basic analytes, namely methadone, fluoxetine, venlafaxine, and tramadol, were selected as model compounds for investigating their stereoselective separation with highly sulfated gamma-cyclodextrin (HS gamma-CD) by capillary electrophoresis (CE)-UV and CE-mass spectrometry (MS).
highly sulfated gamma-cyclodextrin Binding (compounds) of in capillary associated with tramadol, methadone and fluoxetine
2) Confidence 0.01 Published 2003 Journal Electrophoresis Section Abstract Doc Link 12900876 Disease Relevance 0 Pain Relevance 0.30
More recently, palonosetron has gained approval in Europe for the prevention of acute nausea and vomiting associated with HEC, and the prevention of nausea and vomiting associated with MEC.
HEC Binding (associated) of associated with vomiting
3) Confidence 0.01 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2387285 Disease Relevance 1.15 Pain Relevance 0.12

General Comments

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