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Context Info
Confidence 0.45
First Reported 1992
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.10
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SLC12A2) plasma membrane (SLC12A2) transmembrane transport (SLC12A2)
Anatomy Link Frequency
plasma 1
SLC12A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 6 94.04 High High
Catecholamine 1 88.40 High High
opiate 1 67.60 Quite High
pruritus 3 28.20 Quite Low
methotrexate 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 53 87.36 High High
Alkalosis 11 82.80 Quite High
Cancer 23 80.16 Quite High
Hypersensitivity 5 78.72 Quite High
Hypomagnesemia 4 76.60 Quite High
Diarrhoea 5 75.48 Quite High
Toxicity 10 74.76 Quite High
Disease Progression 7 68.36 Quite High
Disease 27 66.84 Quite High
Rectal Cancer 1 63.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The decreased plasma [Cl-] and [K+] in the NAA trial of the present study is consistent with increased activities of the NKCC and Na+-K+-ATPase.
Positive_regulation (increased) of NKCC in plasma
1) Confidence 0.45 Published 2007 Journal Acta Vet Scand Section Body Doc Link PMC2241837 Disease Relevance 0.20 Pain Relevance 0.04
The same individuals demonstrated a consistent increase in NKCC and no change in the expression of Fc receptors.
Positive_regulation (increase) of NKCC
2) Confidence 0.11 Published 1992 Journal Clin. Immunol. Immunopathol. Section Abstract Doc Link 1541057 Disease Relevance 0 Pain Relevance 0.56
A total of 1040 patients were screened, of whom only 463 were randomized (1:1); 231 received panitumumab with BSC, 232 received BSC only, 174 patients received panitumumab under crossover protocol.
Positive_regulation (received) of BSC
3) Confidence 0.09 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012427 Disease Relevance 0.91 Pain Relevance 0

General Comments

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