INT112279

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.07
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos1) aging (Nos1) enzyme binding (Nos1)
cytoplasm (Nos1) cytosol (Nos1) oxidoreductase activity (Nos1)
Anatomy Link Frequency
neurons 2
motoneurons 2
Nos1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventrolateral medulla 55 99.56 Very High Very High Very High
Action potential 1 92.84 High High
tetrodotoxin 3 91.72 High High
conotoxin 1 71.40 Quite High
Neuronal nitric oxide synthase 2 61.16 Quite High
medulla 11 59.84 Quite High
Sciatica 3 25.00 Low Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 3 100.00 Very High Very High Very High
Death 64 94.24 High High
Pressure Volume 2 Under Development 4 91.68 High High
Injury 2 85.64 High High
Poisoning 7 83.12 Quite High
Toxicity 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These properties endow GPN neurons with an exquisite ability to regulate carotid body chemoreceptor function during hypoxia, via voltage-gated Ca2+-entry, activation of nNOS, and release of NO.
Regulation (regulate) of Positive_regulation (activation) of nNOS in neurons associated with hypoxia
1) Confidence 0.39 Published 2005 Journal Neuroscience Section Abstract Doc Link 15802195 Disease Relevance 0.28 Pain Relevance 0.29
Our results provide in vivo evidence that the survival of injured adult mammalian motoneurons can be promoted by specific neurotrophic factors, and that this effect is associated with inhibition of nNOS expression and up-regulation of c-Jun and P75 expression.
Regulation (regulation) of Positive_regulation (regulation) of nNOS in motoneurons
2) Confidence 0.22 Published 2003 Journal J. Neurotrauma Section Abstract Doc Link 12906744 Disease Relevance 0.33 Pain Relevance 0.03
Activation of MEK1/2 or ERK1/2 underlies the augmentation of NOS I or PKG in RVLM during the pro-life phase
Regulation (underlies) of Positive_regulation (augmentation) of NOS I associated with rostral ventrolateral medulla
3) Confidence 0.18 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2848001 Disease Relevance 0.47 Pain Relevance 0.23

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox