INT112325

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Context Info
Confidence 0.41
First Reported 2003
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Vegfa) extracellular space (Vegfa) growth (Vegfa)
extracellular region (Vegfa) cytoplasm (Vegfa)
Anatomy Link Frequency
brain 1
Vegfa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 3 50.00 Quite Low
Inflammation 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 99.48 Very High Very High Very High
Necrosis 2 99.24 Very High Very High Very High
Diabetes Mellitus 28 88.80 High High
Cv General 3 Under Development 1 76.60 Quite High
Cv Unclassified Under Development 3 75.28 Quite High
Diabetic Retinopathy 21 75.00 Quite High
Stress 20 75.00 Quite High
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Ischemia led to strong upregulation of mRNA transcripts for heat shock proteins 70, 27, 105, 86 and 40 kDa, vascular endothelial growth factor, brain-derived neurotrophic factor, plasminogen activator inhibitor-1, activating transcription factor 3, B-cell translocation gene 2, and growth arrest and DNA damage inducible 45 alpha protein compared to the NI tissue.
Transcription (transcripts) of vascular endothelial growth factor in brain
1) Confidence 0.41 Published 2003 Journal Cardiovasc. Res. Section Body Doc Link 12909328 Disease Relevance 0.15 Pain Relevance 0
Real time reverse transcription (RT)–PCR and western blot analyses were performed to evaluate the mRNA and protein levels of Core/emopamil binding protein (C/EBP) homologous protein (CHOP), vascular endothelial growth factor (VEGF), and tumor necrosis factor-?
Transcription (levels) of vascular endothelial growth factor associated with necrosis and cancer
2) Confidence 0.29 Published 2011 Journal Molecular Vision Section Abstract Doc Link PMC3021576 Disease Relevance 0.96 Pain Relevance 0

General Comments

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