INT112363

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.60
First Reported 2001
Last Reported 2010
Negated 3
Speculated 3
Reported most in Body
Documents 6
Total Number 9
Disease Relevance 2.28
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HIF1A) signal transduction (HIF1A) nucleolus (HIF1A)
nucleus (HIF1A) transcription factor binding (HIF1A) cytoplasm (HIF1A)
Anatomy Link Frequency
lung 4
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 4 100.00 Very High Very High Very High
aspirin 4 97.76 Very High Very High Very High
cINOD 12 94.00 High High
ischemia 18 50.00 Quite Low
Angina 7 50.00 Quite Low
Inflammatory response 2 49.52 Quite Low
COX2 1 25.00 Low Low
acular 1 25.00 Low Low
Inflammation 1 21.20 Low Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 21 100.00 Very High Very High Very High
Lung Cancer 4 99.88 Very High Very High Very High
Cancer 6 99.20 Very High Very High Very High
Pneumothorax 4 99.08 Very High Very High Very High
Cv Unclassified Under Development 16 98.48 Very High Very High Very High
Aggression 1 98.36 Very High Very High Very High
Injury 2 95.92 Very High Very High Very High
INFLAMMATION 7 93.72 High High
Reprotox - General 1 2 75.00 Quite High
Death 2 53.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AIM: To investigate the effect of NSAID administration on the expression of HIF-1alpha in human gastric mucosa.
Spec (investigate) Regulation (effect) of Gene_expression (expression) of HIF-1alpha
1) Confidence 0.60 Published 2003 Journal Aliment. Pharmacol. Ther. Section Body Doc Link 12925145 Disease Relevance 0.29 Pain Relevance 0
CONCLUSION: Anesthesia and OLV procedure performed for lung cancer or pneumothorax does not affect the expression of HIF1alpha.
Neg (not) Regulation (affect) of Gene_expression (expression) of HIF1alpha in lung
2) Confidence 0.60 Published 2010 Journal Anticancer Res. Section Body Doc Link 20530420 Disease Relevance 0.13 Pain Relevance 0
PURPOSE: Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are considered to be potential targets for antineoplastic therapy because they regulate the expression of genes that contribute to tumor cell survival, aggressiveness, and angiogenesis.
Regulation (regulate) of Gene_expression (expression) of HIF-1alpha associated with cancer, hypoxia and aggression
3) Confidence 0.44 Published 2003 Journal Clin. Cancer Res. Section Abstract Doc Link 12912967 Disease Relevance 0.67 Pain Relevance 0.38
BACKGROUND/AIM: A prospective study was designed to investigate the effects of anesthesia, particularly that of the one-lung ventilation procedure (OLV), on the expression of hypoxia-inducible factor 1alpha (HIF1alpha) in patients with lung carcinomas and pneumothorax.
Spec (investigate) Regulation (effects) of Gene_expression (expression) of HIF1alpha in lung associated with anesthesia, lung cancer, hypoxia and pneumothorax
4) Confidence 0.44 Published 2010 Journal Anticancer Res. Section Abstract Doc Link 20530420 Disease Relevance 0.45 Pain Relevance 0.10
Helicobacter pylori infection did not affected the levels of HIF-1alpha.
Neg (not) Regulation (affected) of Gene_expression (levels) of HIF-1alpha
5) Confidence 0.26 Published 2003 Journal Aliment. Pharmacol. Ther. Section Body Doc Link 12925145 Disease Relevance 0.17 Pain Relevance 0
The aim of the present study was to analyze the role of iNOS-derived NO in HIF-1alpha stabilization and TFF gene expression in damaged gastric mucosa.
Spec (analyze) Regulation (role) of Gene_expression (expression) of HIF-1alpha
6) Confidence 0.26 Published 2010 Journal FASEB J. Section Abstract Doc Link 19741170 Disease Relevance 0.24 Pain Relevance 0.13
Expression of hypoxia-inducible factor 1 alpha regulated genes was not influenced by cardioplegia and reperfusion, ischemic preconditioning or unstable angina.
Neg (not) Regulation (influenced) of Gene_expression (Expression) of hypoxia-inducible factor 1 alpha
7) Confidence 0.24 Published 2008 Journal Eur J Cardiothorac Surg Section Body Doc Link 18842422 Disease Relevance 0.06 Pain Relevance 0
Expression of hypoxia-inducible factor 1 alpha regulated genes was not influenced by cardioplegia and reperfusion, ischemic preconditioning or unstable angina.
Regulation (regulated) of Gene_expression (Expression) of hypoxia-inducible factor 1 alpha
8) Confidence 0.24 Published 2008 Journal Eur J Cardiothorac Surg Section Body Doc Link 18842422 Disease Relevance 0.06 Pain Relevance 0
Delivery of intracellular modulators for therapeutic angiogenesis, including transcription factors that control angiogenesis such as hypoxia inducible factor-1 alpha (HIF-1?)
Regulation (control) of Gene_expression (angiogenesis) of hypoxia inducible factor-1 alpha associated with hypoxia
9) Confidence 0.13 Published 2001 Journal Curr Control Trials Cardiovasc Med Section Body Doc Link PMC64829 Disease Relevance 0.21 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox