INT112420

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Context Info
Confidence 0.16
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.85
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (FKBP5) protein folding (FKBP5) nucleolus (FKBP5)
nucleus (FKBP5) cytoplasm (FKBP5)
FKBP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 14 99.18 Very High Very High Very High
COX2 4 98.86 Very High Very High Very High
Disease Link Frequency Relevance Heat
Reprotox - General 1 6 96.04 Very High Very High Very High
Cancer 2 90.68 High High
INFLAMMATION 4 88.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that two cyclooxygenase 2-specific NSAIDs, celecoxib and nimesulide, dramatically reduced the expression of androgen-inducible genes, such as prostate-specific antigen, hK2, and the FK506-binding protein 51 (FKBP51).
Negative_regulation (reduced) of Gene_expression (expression) of FK506-binding protein 51 associated with cinod and cox2
1) Confidence 0.16 Published 2003 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 12917209 Disease Relevance 0.43 Pain Relevance 0.71
We found that two cyclooxygenase 2-specific NSAIDs, celecoxib and nimesulide, dramatically reduced the expression of androgen-inducible genes, such as prostate-specific antigen, hK2, and the FK506-binding protein 51 (FKBP51).
Negative_regulation (reduced) of Gene_expression (expression) of FKBP51 associated with cinod and cox2
2) Confidence 0.16 Published 2003 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 12917209 Disease Relevance 0.43 Pain Relevance 0.71

General Comments

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