INT112506

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Context Info
Confidence 0.64
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 16.71
Pain Relevance 1.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (HGF) extracellular space (HGF) extracellular region (HGF)
cell morphogenesis (HGF)
Anatomy Link Frequency
HGF 11
hepatocyte 1
heart 1
HGF (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 5 99.92 Very High Very High Very High
Angina 14 99.84 Very High Very High Very High
alcohol 48 86.68 High High
Pain 12 79.84 Quite High
Inflammation 54 50.00 Quite Low
cytokine 42 50.00 Quite Low
dexamethasone 4 50.00 Quite Low
antagonist 2 34.08 Quite Low
fibrosis 24 23.52 Low Low
Inflammatory stimuli 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis 264 99.96 Very High Very High Very High
Stable Angina Pectoris 8 99.84 Very High Very High Very High
Chronic Hepatitis 248 99.28 Very High Very High Very High
Fibrosis 72 99.28 Very High Very High Very High
Dog Diseases 8 98.92 Very High Very High Very High
Cv General 3 Under Development 6 98.84 Very High Very High Very High
Myocardial Infarction 1 98.80 Very High Very High Very High
Cirrhosis 456 98.76 Very High Very High Very High
Infection 43 98.48 Very High Very High Very High
Hiv-narrow Range Search Term 128 97.04 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Differences in mRNA expression of IDO, HGF, COX2 and CIITA was consistently observed (Figure 5A).
Transcription (expression) of HGF in HGF associated with cox2
1) Confidence 0.64 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814860 Disease Relevance 0.08 Pain Relevance 0.09
The increased mRNA levels of HGF and the decreased levels of c-MET mRNA in fibrotic canine diseases (CH, LDH, and CIRR), were in line with publications from human samples [20].
Transcription (levels) of HGF in HGF associated with dog diseases, fibrosis, chronic hepatitis and cirrhosis
2) Confidence 0.58 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.28 Pain Relevance 0
The increased mRNA levels of HGF and the decreased levels of c-MET mRNA in fibrotic canine diseases (CH, LDH, and CIRR), were in line with publications from human samples [20].
Transcription (levels) of HGF in HGF associated with dog diseases, fibrosis, chronic hepatitis and cirrhosis
3) Confidence 0.56 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.34 Pain Relevance 0
DEX inhibited HGF mRNA and COX-2 mRNA.
Transcription (mRNA) of HGF in HGF
4) Confidence 0.53 Published 2003 Journal Aliment. Pharmacol. Ther. Section Body Doc Link 12925150 Disease Relevance 0 Pain Relevance 0
HGF levels in SAP group correlated with heart failure symptoms (p=0,023).
Transcription (levels) of HGF in heart associated with angina and myocardial infarction
5) Confidence 0.50 Published 2003 Journal Pol. Arch. Med. Wewn. Section Abstract Doc Link 16736998 Disease Relevance 1.36 Pain Relevance 1.25
Canine specific mRNA expression of the regenerative hepatocyte growth factor (HGF) signaling pathway and relevant down-stream pathways were measured by semi-quantitative PCR and Western blot (STAT3, PKB, ERK1/2, and p38-MAPK).
Transcription (expression) of HGF in HGF
6) Confidence 0.43 Published 2007 Journal Comp Hepatol Section Abstract Doc Link PMC1971050 Disease Relevance 1.76 Pain Relevance 0
Towards healthy control samples HGF mRNA levels were significantly induced in CH, LDH, and CIRR, three-, five-, and five-fold, respectively (Figure 2A).
Transcription (levels) of HGF in HGF associated with chronic hepatitis and cirrhosis
7) Confidence 0.43 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.71 Pain Relevance 0.04
Statistically significant differences (ANOVA) were identified in the expression of mRNA encoding HGF (P < .001) and c-MET (P < .001).
Transcription (expression) of HGF in HGF
8) Confidence 0.43 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.69 Pain Relevance 0.04
In AH, HGF mRNA levels remained unchanged toward healthy control.
Transcription (levels) of HGF in HGF associated with hepatitis
9) Confidence 0.43 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.78 Pain Relevance 0.04
There is a clear quantitative correlation between HGF protein and mRNA levels, as both HGF mRNA and protein levels are increased in CH, LDH, and CIRR.
Transcription (levels) of HGF in HGF associated with chronic hepatitis and cirrhosis
10) Confidence 0.43 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.73 Pain Relevance 0.03
Canine specific mRNA expression of the regenerative hepatocyte growth factor (HGF) signaling pathway and relevant down-stream pathways were measured by semi-quantitative PCR and Western blot (STAT3, PKB, ERK1/2, and p38-MAPK).
Transcription (expression) of hepatocyte growth factor in HGF
11) Confidence 0.43 Published 2007 Journal Comp Hepatol Section Abstract Doc Link PMC1971050 Disease Relevance 1.76 Pain Relevance 0
EGF-R, epithelial growth factor receptor; HMG-CoA, 3-Hydroxy-3-methylglutaryl-coenzyme A; VEGF-R, vascular endothelial growth factor receptor; MVD, microvascular density; PDGF-R, platelet derived growth factor receptor; HGF, hepatocyte growth factor receptor

Authors contributions

Transcription (contributions) of hepatocyte growth factor in hepatocyte
12) Confidence 0.10 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149419 Disease Relevance 0.33 Pain Relevance 0
The summary scores of the SF-36 have been shown to be responsive
Transcription (scores) of SF-36
13) Confidence 0.03 Published 2003 Journal Health Qual Life Outcomes Section Body Doc Link PMC183842 Disease Relevance 1.53 Pain Relevance 0.13
EGF-R, epithelial growth factor receptor; HMG-CoA, 3-Hydroxy-3-methylglutaryl-coenzyme A; VEGF-R, vascular endothelial growth factor receptor; MVD, microvascular density; PDGF-R, platelet derived growth factor receptor; HGF, hepatocyte growth factor receptor

Authors contributions

Transcription (contributions) of hepatocyte growth factor in HGF
14) Confidence 0.03 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149419 Disease Relevance 0.33 Pain Relevance 0

General Comments

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