INT112626

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 2003
Last Reported 2008
Negated 0
Speculated 2
Reported most in Abstract
Documents 5
Total Number 11
Disease Relevance 8.03
Pain Relevance 4.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
nerve 1
wrist 1
Cts (Mus musculus)
Pain Link Frequency Relevance Heat
carpal tunnel syndrome 368 100.00 Very High Very High Very High
rheumatoid arthritis 2 99.50 Very High Very High Very High
corticosteroid 2 98.98 Very High Very High Very High
ischemia 5 97.64 Very High Very High Very High
palliative 9 94.04 High High
Pain 2 90.64 High High
backache 1 30.56 Quite Low
headache 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carpal Tunnel Syndrome 433 100.00 Very High Very High Very High
Metabolic Syndrome 24 99.84 Very High Very High Very High
Hypertension 2 99.80 Very High Very High Very High
Rheumatoid Arthritis 2 99.50 Very High Very High Very High
Hyperglycemia 2 99.44 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

2 99.14 Very High Very High Very High
Thyroid Disease 2 98.06 Very High Very High Very High
Diabetes Mellitus 2 97.74 Very High Very High Very High
Cv Unclassified Under Development 5 97.64 Very High Very High Very High
Injury 15 94.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The risk of CTS was statistically significantly increased for every 10 hours of repetitive work (OR = 1.86 (95% CI 1.06–3.19)) after adjusting for forceful work and personal characteristics.
Positive_regulation (increased) of CTS associated with carpal tunnel syndrome
1) Confidence 0.59 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2569035 Disease Relevance 0.43 Pain Relevance 0.35
It is widely believed that biomechanical factors (e.g. forceful exertions, repetition, and awkward postures) increase the risk of CTS by increasing carpal canal pressure with subsequent nerve ischemia [27].
Positive_regulation (increase) of CTS in nerve associated with ischemia and carpal tunnel syndrome
2) Confidence 0.59 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2569035 Disease Relevance 0.54 Pain Relevance 0.32
CTs were mostly provided by volunteers, and at most settings, limited or no funding was available.
Positive_regulation (provided) of CTs
3) Confidence 0.40 Published 2007 Journal Support Care Cancer Section Body Doc Link 17609996 Disease Relevance 0 Pain Relevance 0
These data indicate a steady increase in CTS over the last decade.
Positive_regulation (increase) of CTS associated with carpal tunnel syndrome
4) Confidence 0.40 Published 2007 Journal Med Lav Section Abstract Doc Link 17679345 Disease Relevance 0.76 Pain Relevance 0.77
There is insufficient epidemiological evidence that computer work causes CTS.



Positive_regulation (causes) of CTS associated with carpal tunnel syndrome
5) Confidence 0.40 Published 2008 Journal BMC Musculoskelet Disord Section Abstract Doc Link PMC2569035 Disease Relevance 0.43 Pain Relevance 0.34
CTS is generally believed to be caused by increased pressure in the carpal tunnel.
Positive_regulation (caused) of CTS associated with carpal tunnel syndrome
6) Confidence 0.40 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2569035 Disease Relevance 0.85 Pain Relevance 0.42
In summary, because of insufficient quality, bias, lack of consistency and statistical power evidence is insufficient to conclude that computer work (mouse and keyboard) causes CTS.
Positive_regulation (causes) of CTS associated with carpal tunnel syndrome
7) Confidence 0.40 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2569035 Disease Relevance 0.51 Pain Relevance 0.35
Metabolic syndrome includes abdominal obesity, dyslipidemia, hyperglycemia, and hypertension that may cause CTS.
Spec (may) Positive_regulation (cause) of CTS associated with hyperglycemia, hypertension, carpal tunnel syndrome and metabolic syndrome
8) Confidence 0.38 Published 2007 Journal Acta Neurol. Scand. Section Abstract Doc Link 17661797 Disease Relevance 2.00 Pain Relevance 0.90
Many factors such as diabetes mellitus, hypothyroidism, hormonal replacement therapy, corticosteroid use, rheumatoid arthritis and wrist fractures may cause CTS.
Spec (may) Positive_regulation (cause) of CTS in wrist associated with corticosteroid, diabetes mellitus, thyroid disease, carpal tunnel syndrome and rheumatoid arthritis
9) Confidence 0.38 Published 2007 Journal Acta Neurol. Scand. Section Abstract Doc Link 17661797 Disease Relevance 1.84 Pain Relevance 0.82
As a result, the last decade has seen an increase in the integration and usage of CTs, as adjunct therapies to conventional medical treatment.
Positive_regulation (increase) of CTs
10) Confidence 0.34 Published 2005 Journal Int J Palliat Nurs Section Abstract Doc Link 15944500 Disease Relevance 0.41 Pain Relevance 0.31
Taken together, these results suggest that cNOS activation seems to be more implicated in the 5% CTS modulation of proteoglycan production than iNOS activation.
Positive_regulation (activation) of CTS
11) Confidence 0.03 Published 2003 Journal J. Cell. Biochem. Section Abstract Doc Link 12938164 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox