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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.52

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mitochondrion (Cpox) intracellular (TNF) extracellular matrix organization (TNF)
cytoplasm (Cpox) extracellular space (TNF) signal transduction (TNF)
Cpox (Rattus norvegicus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 100.00 Very High Very High Very High
diclofenac 2 95.92 Very High Very High Very High
acular 2 94.72 High High
adenocard 2 88.04 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 85.56 High High
Immunization 3 83.00 Quite High
Immunotherapy Of Cancer 3 75.00 Quite High
Necrosis 1 70.76 Quite High
Cancer 3 70.40 Quite High
Malignant Neoplastic Disease 1 60.20 Quite High
Adenocarcinoma 1 47.52 Quite Low
Gastrointestinal Neoplasms 1 45.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since cyclooxygenase, COX, is the rate-controlling enzyme in PGE production, COX inhibitors, otherwise known as non-steroidal anti-inflammatory drugs (NSAID), increase TNF synthesis and release by depriving AC of PGE.
COX Positive_regulation (increase) of Gene_expression (synthesis) of TNF associated with inflammation and cinod
1) Confidence 0.01 Published 2003 Journal Mol. Immunol. Section Abstract Doc Link 12943802 Disease Relevance 0.79 Pain Relevance 0.52

General Comments

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