INT112703

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Context Info
Confidence 0.37
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.64
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Accn2)
Anatomy Link Frequency
nervous system 2
Accn2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ASIC 111 100.00 Very High Very High Very High
ischemia 62 87.76 High High
nociceptor 2 80.96 Quite High
Hippocampus 12 80.16 Quite High
Pain 3 79.76 Quite High
tolerance 7 64.48 Quite High
GABAergic 3 26.32 Quite Low
imagery 7 5.00 Very Low Very Low Very Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acidosis 13 93.64 High High
Cv Unclassified Under Development 58 87.76 High High
Pain 3 79.76 Quite High
Injury 6 79.60 Quite High
Brain Hemorrhage 4 50.00 Quite Low
Death 9 36.64 Quite Low
Apoptosis 5 35.84 Quite Low
Stroke 3 29.00 Quite Low
Epilepsy 4 5.00 Very Low Very Low Very Low
Convulsion 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The acid-sensitive ion channel 1 (ASIC1alpha or BNaC2a) is the most abundant of all mammalian proton-gated ion channels and the one that has the broadest distribution in the nervous system.
ion channel 1 Binding (abundant) of in nervous system
1) Confidence 0.37 Published 2003 Journal J. Biol. Chem. Section Abstract Doc Link 12947112 Disease Relevance 0.08 Pain Relevance 0.16
The acid-sensitive ion channel 1 (ASIC1alpha or BNaC2a) is the most abundant of all mammalian proton-gated ion channels and the one that has the broadest distribution in the nervous system.
ASIC1 Binding (abundant) of in nervous system
2) Confidence 0.36 Published 2003 Journal J. Biol. Chem. Section Abstract Doc Link 12947112 Disease Relevance 0.08 Pain Relevance 0.16
Hippocampal NG2 glia have ASIC1a immunoreactivity
ASIC1a Binding (immunoreactivity) of
3) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2937019 Disease Relevance 0 Pain Relevance 0.16
Association with ASIC 2a also slows the inactivation kinetics of ASIC 1a and increases its selectivity for Na+ over Ca2+ [32–34].
ASIC Binding (Association) of associated with asic
4) Confidence 0.10 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2820994 Disease Relevance 0.49 Pain Relevance 0.71

General Comments

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