INT112800

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.48
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CASP1, CCL2) signal transduction (CASP1, CCL2) aging (CCL2)
intracellular (CASP1) cytosol (CASP1) peptidase activity (CASP1)
Anatomy Link Frequency
smooth muscle cells 2
CASP1 (Homo sapiens)
CCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 98.00 Very High Very High Very High
chemokine 4 92.72 High High
adenocard 6 82.44 Quite High
cINOD 2 27.28 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 98.00 Very High Very High Very High
Asthma 2 94.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Modulation by cAMP of IL-1beta-induced eotaxin and MCP-1 expression and release in human airway smooth muscle cells.
IL-1beta-induced Positive_regulation (induced) of Gene_expression (expression) of MCP-1 in smooth muscle cells
1) Confidence 0.04 Published 2003 Journal Eur. Respir. J. Section Title Doc Link 12952251 Disease Relevance 0.29 Pain Relevance 0.22
Prostaglandin E2, known as an activator of the prostanoid receptors EP2 and EP4, which are positively coupled to adenylyl cyclase, also decreased the IL-1beta-induced eotaxin and MCP-1 production by 57+/-17 and 53+/-4%, respectively.
IL-1beta-induced Positive_regulation (induced) of Gene_expression (production) of MCP-1
2) Confidence 0.04 Published 2003 Journal Eur. Respir. J. Section Abstract Doc Link 12952251 Disease Relevance 0.19 Pain Relevance 0.21

General Comments

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