INT112874

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Context Info
Confidence 0.23
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.42
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Plcb1) signal transduction (Plcb1) cell adhesion (Plcb1)
mRNA processing (Plcb1) nucleus (Plcb1) enzyme binding (Plcb1)
Anatomy Link Frequency
neurons 1
Plcb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 4 99.86 Very High Very High Very High
Dorsal horn 1 99.48 Very High Very High Very High
Inflammation 4 96.44 Very High Very High Very High
tail-flick 1 89.48 High High
Acute pain 1 87.80 High High
Pain 7 80.64 Quite High
IPN 3 78.32 Quite High
Glutamate receptor 2 75.00 Quite High
antagonist 1 71.92 Quite High
Intracerebroventricular 1 69.36 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 8 97.92 Very High Very High Very High
INFLAMMATION 2 96.44 Very High Very High Very High
Nociception 4 92.84 High High
Pain 6 87.80 High High
Inflammatory Pain 3 78.32 Quite High
Syndrome 8 51.68 Quite High
Disease 25 46.96 Quite Low
Infection 53 29.64 Quite Low
Sprains And Strains 51 5.00 Very Low Very Low Very Low
Viral Meningitis 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The genes that encode the key virulence factors PlcA, LLO, ActA, and PlcB are clustered in a 10?
Gene_expression (encode) of PlcB
1) Confidence 0.23 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2829626 Disease Relevance 0.05 Pain Relevance 0
In the dorsal horn of the spinal cord where PLCbeta1 and PLCbeta4 mRNAs are expressed, no difference was found between the wild-type and knock-out mice in the number of Fos-like immunoreactive neurons, which represent neuronal activity in the second phase in the formalin test.
Gene_expression (expressed) of PLCbeta1 in neurons associated with targeted disruption, dorsal horn and spinal cord
2) Confidence 0.05 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12954872 Disease Relevance 1.37 Pain Relevance 0.86

General Comments

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