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Context Info
Confidence 0.32
First Reported 2003
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Crhr2) endoplasmic reticulum (Crhr2) plasma membrane (Crhr2)
signal transducer activity (Crhr2)
Crhr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 4 99.44 Very High Very High Very High
nud 2 75.00 Quite High
Hyperalgesia 1 25.00 Low Low
Bioavailability 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 8 92.40 High High
Dyspepsia 2 75.00 Quite High
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A novel water-soluble tricyclic CRF1 antagonist, NBI 35965 was developed that displayed a high affinity for CRF1 (Ki approximately 4 nM) while having no binding affinity to CRF2.
CRF2 Neg (no) Binding (affinity) of associated with antagonist
1) Confidence 0.32 Published 2003 Journal Brain Res. Section Abstract Doc Link 12957366 Disease Relevance 0.33 Pain Relevance 0.17

General Comments

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