INT112975

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Context Info
Confidence 0.70
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (Ucp1) mitochondrion (Ucp1) transmembrane transport (Ucp1)
Anatomy Link Frequency
adipose tissue 1
Ucp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 5 79.08 Quite High
Disease Link Frequency Relevance Heat
Obesity 4 98.92 Very High Very High Very High
Body Weight 1 97.80 Very High Very High Very High
Chronic Renal Failure 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, we demonstrated that exposure of bilateral renal denervated or of renal chronic capsaicin-treated rats to a similar experimental protocol results in a fast and high rise in rectal temperature response, and this is associated with a significant increase in the basal serine phosphorylation and protein levels of Akt and protein levels of UCP1.
Positive_regulation (increase) of UCP1
1) Confidence 0.70 Published 2008 Journal Nephrol. Dial. Transplant. Section Body Doc Link 18593740 Disease Relevance 0 Pain Relevance 0
Two-week treatment of capsiate increased the levels of UCP1 protein and mRNA in brown adipose tissue and UCP2 mRNA in white adipose tissue.
Positive_regulation (increased) of UCP1 in adipose tissue associated with obesity
2) Confidence 0.28 Published 2003 Journal J. Appl. Physiol. Section Abstract Doc Link 12959953 Disease Relevance 0.47 Pain Relevance 0.15

General Comments

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