INT112990

Context Info Confidence 0.10 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.59 Pain Relevance 0.09

unfolded protein binding (AIP) cytoplasm (AIP) signal transducer activity (AIP) cytosol (AIP) signal transduction (AIP) nucleolus (AIP)

Anatomy Link Frequency fibroblasts 1 AIP (Homo sapiens)

Pain Link Frequency Relevance Heat palliative 1 93.84

Disease Link Frequency Relevance Heat Porphyria 8 100.00 Disease 1 90.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

An initial step towards gene therapy was recently taken by showing that PBGD could be expressed to correct the enzyme deficiency in AIP fibroblasts.

Negative_regulation (deficiency) of AIP in fibroblasts associated with porphyria

1) Confidence 0.10 Published 2003 Journal Mol. Cell. Biochem. Section Abstract Doc Link 12962144 Disease Relevance 0.59 Pain Relevance 0.09

General Comments

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