INT113061

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Context Info
Confidence 0.49
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cdk20) cell cycle (Cdk20) cilium (Cdk20)
cell division (Cdk20) kinase activity (Cdk20) cytoplasm (Cdk20)
Cdk20 (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 2 99.30 Very High Very High Very High
agonist 1 97.36 Very High Very High Very High
Morphine 11 88.40 High High
tolerance 5 75.00 Quite High
Analgesic 3 75.00 Quite High
analgesia 1 71.52 Quite High
Anterior cingulate 3 66.56 Quite High
Locus ceruleus 3 60.88 Quite High
Nucleus accumbens 1 55.20 Quite High
amygdala 4 52.80 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Opioid-receptor activation in cell lines results in phosphorylation of p42/44 mitogen-activated protein kinase (MAPK), which contributes to agonist-induced desensitization of adenylate cyclase signaling.
Positive_regulation (results) of Phosphorylation (phosphorylation) of p42 associated with agonist and opioid
1) Confidence 0.49 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12967998 Disease Relevance 0 Pain Relevance 0.78

General Comments

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