INT113144

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Context Info
Confidence 0.59
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.05
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nr4a1) DNA binding (Nr4a1)
Anatomy Link Frequency
telencephalic 2
Nr4a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 13 100.00 Very High Very High Very High
Nucleus accumbens 19 99.44 Very High Very High Very High
Nerve growth factor 1 95.08 Very High Very High Very High
amygdala 42 93.88 High High
Hippocampus 25 91.20 High High
Dynorphin 6 89.92 High High
agonist 1 49.68 Quite Low
Dopamine 2 25.00 Low Low
Thalamus 5 6.12 Low Low
Eae 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 59 99.98 Very High Very High Very High
Cognitive Disorder 4 83.28 Quite High
Parkinson's Disease 1 75.00 Quite High
Aids-related Complex 14 66.48 Quite High
Hypersensitivity 8 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Overweight 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ensure cues increased ngfi-b mRNA levels in telencephalic regions (see Additional file 3).
Positive_regulation (increased) of Transcription (levels) of ngfi-b in telencephalic
1) Confidence 0.59 Published 2007 Journal BMC Biol Section Body Doc Link PMC1868707 Disease Relevance 0.23 Pain Relevance 0.37
The denervation process induced an increase of NGFI-B and enkephalin (ENK) mRNA levels and the increase of NGFI-B took place predominantly in ENK-containing cells.
Positive_regulation (increase) of Transcription (levels) of NGFI-B associated with enkephalin
2) Confidence 0.46 Published 2003 Journal Neurobiol. Dis. Section Abstract Doc Link 13678671 Disease Relevance 0.07 Pain Relevance 0.51
This pregnancy-related attenuation of PVN activation is consistent with data comparing virgin and late pregnant mice showing reduced stress-induced nur77 mRNA expression (Douglas et al., 2003).
Positive_regulation (induced) of Transcription (expression) of nur77 associated with stress
3) Confidence 0.43 Published 2010 Journal Brain Research Section Body Doc Link PMC2994639 Disease Relevance 0.74 Pain Relevance 0

General Comments

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