INT113243

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Context Info
Confidence 0.23
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNF, OPRM1) Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1)
intracellular (TNF) extracellular matrix organization (TNF) signal transducer activity (OPRM1)
Anatomy Link Frequency
B cells 2
TNF (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 4 100.00 Very High Very High Very High
cytokine 1 99.98 Very High Very High Very High
IPN 1 92.48 High High
Inflammation 2 89.72 High High
Endogenous opioid 1 88.12 High High
Opioid 2 83.04 Quite High
mu opioid receptor 1 65.28 Quite High
Potency 1 26.32 Quite Low
analgesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 5 100.00 Very High Very High Very High
Necrosis 5 100.00 Very High Very High Very High
Inflammatory Pain 1 92.48 High High
INFLAMMATION 2 89.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Herein, we report that in primary human T lymphocytes, Raji B cells, U937 monocytes, primary human polymorphonuclear leukocytes, and mature dendritic cells, the proinflammatory cytokine tumor necrosis factor induced mu-opioid receptor gene transcription.
tumor necrosis factor Positive_regulation (induced) of Transcription (transcription) of mu-opioid receptor gene in B cells associated with necrosis, cancer, opioid receptor and cytokine
1) Confidence 0.23 Published 2003 Journal Mol. Pharmacol. Section Abstract Doc Link 14500744 Disease Relevance 0.84 Pain Relevance 0.51

General Comments

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