INT113268

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Context Info
Confidence 0.15
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.23
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Timp1) extracellular region (Timp1) proteinaceous extracellular matrix (Timp1)
Anatomy Link Frequency
cerebrospinal fluid 2
Timp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
headache 3 100.00 Very High Very High Very High
metalloproteinase 28 97.52 Very High Very High Very High
Central nervous system 1 94.72 High High
carpal tunnel syndrome 2 94.60 High High
Inflammation 3 93.28 High High
Multiple sclerosis 3 84.44 Quite High
Disease Link Frequency Relevance Heat
Contracture 8 99.98 Very High Very High Very High
Dupuytren's Disease 16 99.70 Very High Very High Very High
Disease 14 98.16 Very High Very High Very High
Carpal Tunnel Syndrome 2 94.60 High High
INFLAMMATION 3 93.28 High High
Headache 1 86.28 High High
Demyelinating Disease 3 84.44 Quite High
Neurological Disease 3 82.52 Quite High
Fibrosis 2 66.84 Quite High
Fibroma 6 62.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with Dupuytren's contracture presented with a TIMP-1 concentration of 437 +/- 160 ng/ml, a significantly higher TIMP-1 concentration than that seen in the control patients, who had a concentration of 321 +/- 70 ng/ml (p < 0.05).
Positive_regulation (presented) of Positive_regulation (concentration) of TIMP-1 associated with dupuytren's disease and contracture
1) Confidence 0.15 Published 2003 Journal Plast. Reconstr. Surg. Section Abstract Doc Link 14504511 Disease Relevance 1.19 Pain Relevance 0.28
Patients with Dupuytren's contracture presented with a TIMP-1 concentration of 437 +/- 160 ng/ml, a significantly higher TIMP-1 concentration than that seen in the control patients, who had a concentration of 321 +/- 70 ng/ml (p < 0.05).
Positive_regulation (presented) of Positive_regulation (concentration) of TIMP-1 associated with dupuytren's disease and contracture
2) Confidence 0.15 Published 2003 Journal Plast. Reconstr. Surg. Section Abstract Doc Link 14504511 Disease Relevance 1.21 Pain Relevance 0.28
Elevated levels of MMP-9 and TIMP-1 in the cerebrospinal fluid of neuro-Beh├žet's disease.
Positive_regulation (Elevated) of Positive_regulation (levels) of TIMP-1 in cerebrospinal fluid associated with headache and disease
3) Confidence 0.07 Published 2009 Journal Clin. Exp. Rheumatol. Section Title Doc Link 19796534 Disease Relevance 0.83 Pain Relevance 0.87

General Comments

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