INT113343

Context Info Confidence 0.11 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.14 Pain Relevance 0

mitochondrion (TP53, BAX) nucleus (TP53, BAX) endoplasmic reticulum (TP53, BAX) cytoplasm (TP53, BAX) cytosol (TP53, BAX) cell differentiation (TP53)

TP53 (Homo sapiens) BAX (Homo sapiens)

Pain Link Frequency Relevance Heat aspirin 4 50.00 COX2 1 10.00 cINOD 2 5.00

Disease Link Frequency Relevance Heat Mouth Cancer 2 71.52 Apoptosis 2 70.16 Cancer 1 5.00 INFLAMMATION 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the meanwhile, phosphorylation of p53 at serine 15, accumulation of p53 and increased the expression of its downstream target genes, p21 and Bax induced by ASA.

Phosphorylation (phosphorylation) of p53 Positive_regulation (increased) of Gene_expression (expression) of Bax

1) Confidence 0.11 Published 2003 Journal Eur. J. Clin. Invest. Section Body Doc Link 14511359 Disease Relevance 0.14 Pain Relevance 0

General Comments

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