INT113391

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Context Info
Confidence 0.35
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tacr1) plasma membrane (Tacr1) cytoplasm (Tacr1)
signal transducer activity (Tacr1)
Tacr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 31 99.98 Very High Very High Very High
antagonist 6 77.28 Quite High
IPN 1 75.00 Quite High
Face pain 1 73.84 Quite High
Inflammatory mediators 2 32.92 Quite Low
substance P 22 18.16 Low Low
Inflammatory response 4 17.92 Low Low
Pain 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 35 99.98 Very High Very High Very High
Nociception 1 98.84 Very High Very High Very High
Peripheral Arterial Disease 1 81.80 Quite High
Inflammatory Pain 1 75.00 Quite High
Facial Pain 1 73.84 Quite High
Cystitis 15 31.48 Quite Low
Targeted Disruption 2 16.28 Low Low
Overactive Bladder 7 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulatory network downstream of NK1R activation
Regulation (Regulatory) of Positive_regulation (activation) of NK1R
1) Confidence 0.35 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0 Pain Relevance 0
These data suggest that persistent nociceptive effects associated with orofacial cutaneous inflammation depend at least in part on the activation of NK1R.
Regulation (depend) of Positive_regulation (activation) of NK1R associated with nociception and inflammation
2) Confidence 0.27 Published 2003 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 14517596 Disease Relevance 0.50 Pain Relevance 0.27

General Comments

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