INT113471

Context Info Confidence 0.01 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.43

cell proliferation (RETNLB) extracellular region (RETNLB) molecular_function (RETNLB) cellular_component (RETNLB) cytoplasm (MMP14)

RETNLB (Homo sapiens) MMP14 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 3 100.00 cytokine 4 99.96 Chronic pancreatitis 1 87.04 metalloproteinase 2 75.00

Disease Link Frequency Relevance Heat INFLAMMATION 3 100.00 Pancreatitis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In conclusion, in human pancreatic periacinar myofibroblasts, MMP-1 secretion was regulated by the pro-inflammatory cytokines via the MEK/ERK cascade.

pro-inflammatory Regulation (regulated) of Localization (secretion) of MMP-1 associated with inflammation and cytokine

1) Confidence 0.01 Published 2003 Journal Pancreatology Section Abstract Doc Link 14526152 Disease Relevance 0.24 Pain Relevance 0.43

General Comments

This test has worked.