INT11363

Context Info Confidence 0.27 First Reported 1992 Last Reported 1992 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.87 Pain Relevance 0.46

peptidase activity (PLAT) protein modification process (PLAT) extracellular space (PLAT) extracellular region (PLAT) cytoplasm (PLAT)

PLAT (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 1 100.00 Inflammation 1 100.00 Osteoarthritis 5 95.48 rheumatoid arthritis 5 94.52

Disease Link Frequency Relevance Heat INFLAMMATION 1 100.00 Osteoarthritis 5 95.48 Rheumatoid Arthritis 6 94.52 Arthritis 2 77.92

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effect of therapeutic and pharmacological concentrations of tiaprofenic acid, a non-steroidal anti-inflammatory drug (NSAID), on the synthesis of the plasminogen activators, urokinase plasminogen activator (uPA) and tissue plasminogen activator (tPA), and the plasminogen activator inhibitors 1 and 2 (PAI-1 and PAI-2), by human synovial membranes isolated from osteoarthritis (OA) and rheumatoid arthritis (RA) sufferers was evaluated.

Regulation (effect) of Gene_expression (synthesis) of tPA associated with inflammation, rheumatoid arthritis, cinod and osteoarthritis

1) Confidence 0.27 Published 1992 Journal Br. J. Rheumatol. Section Abstract Doc Link 1555050 Disease Relevance 0.87 Pain Relevance 0.46

General Comments

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