INT113641

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.57
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.20
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (GP1BA) plasma membrane (GP1BA)
Anatomy Link Frequency
platelets 6
GP1BA (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 6 91.60 High High
Angina 4 90.12 High High
anesthesia 2 75.00 Quite High
agonist 1 50.00 Quite Low
withdrawal 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhage 3 99.32 Very High Very High Very High
Cataract 1 96.76 Very High Very High Very High
Sensorineural Hearing Loss 1 95.28 Very High Very High Very High
Alport Syndrome 1 94.16 High High
Bronchitis 42 94.12 High High
Headache 6 91.60 High High
Dyspnea 4 91.24 High High
Thrombocytopenia 4 90.60 High High
Vomiting 4 90.40 High High
Angina 4 90.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tendency to bleeding is highly variable and is due to decreased expression of the GP1b-V-IX complex on the surface of platelets, leading to altered platelet-vessel wall and platelet-platelet interactions.
Negative_regulation (decreased) of Gene_expression (expression) of GP1b in platelet associated with hemorrhage
1) Confidence 0.57 Published 2003 Journal Rev Esp Anestesiol Reanim Section Abstract Doc Link 14552110 Disease Relevance 0.99 Pain Relevance 0.07
RESULTS: AA, ADP, and TRAP-6 markedly increased the expression of CD62P on platelets, whereas CD42b (shedding) and PAC-1 (heterotypic conjugates) expression decreased.
Negative_regulation (decreased) of Gene_expression (expression) of CD42b in platelets
2) Confidence 0.43 Published 2008 Journal Anesth. Analg. Section Body Doc Link 18499605 Disease Relevance 0 Pain Relevance 0
HES200/0.5 and HES130/0.4 reduced the CD42b, CD41/61 and CD62p expression of ADP-agonist-activated platelets at 15 min after intravenous infusion.
Negative_regulation (reduced) of Gene_expression (expression) of CD42b in platelets
3) Confidence 0.20 Published 2006 Journal Acta Anaesthesiol Scand Section Body Doc Link 16987338 Disease Relevance 0 Pain Relevance 0
Secondary efficacy variables were: treatment response according to three criteria (BSS total score of <3 on day 7, decrease in BSS total score of at least 7 points from day 0 to day 7 and BSS total score <3 on day 7 combined with a decrease in BSS total score of at least 7 points from day 0 to day 7), onset of effect, change in the total score of individual symptoms and, change of general symptoms (e.g.
Negative_regulation (were) of Gene_expression (change) of BSS total score
4) Confidence 0.05 Published 2010 Journal Acta Paediatrica (Oslo, Norway : 1992) Section Body Doc Link PMC2855831 Disease Relevance 0.61 Pain Relevance 0.18
Secondary efficacy variables were: treatment response according to three criteria (BSS total score of <3 on day 7, decrease in BSS total score of at least 7 points from day 0 to day 7 and BSS total score <3 on day 7 combined with a decrease in BSS total score of at least 7 points from day 0 to day 7), onset of effect, change in the total score of individual symptoms and, change of general symptoms (e.g.
Negative_regulation (were) of Gene_expression (change) of BSS total score
5) Confidence 0.05 Published 2010 Journal Acta Paediatrica (Oslo, Norway : 1992) Section Body Doc Link PMC2855831 Disease Relevance 0.61 Pain Relevance 0.18

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox