INT11366

Context Info Confidence 0.33 First Reported 1992 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 1.60 Pain Relevance 0.22

transport (MB)

Anatomy Link Frequency myocardial cell 2 skeletal muscle cells 2 MB (Homo sapiens)

Pain Link Frequency Relevance Heat Angina 3 98.60 ischemia 1 91.76 Pain 1 33.28 Inflammation 1 27.20

Disease Link Frequency Relevance Heat Disorders Of Creatine Metabolism 5 100.00 Cv Unclassified Under Development 3 99.96 Syndrome 1 99.04 Cv General 3 Under Development 2 98.60 Rhabdomyolysis 7 98.26 Injury 1 95.84 Pathologic Constriction 1 92.16 Poisoning 4 76.72 Coronary Artery Disease 2 75.00 Myalgia 1 33.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Rhabdomyolysis is a clinical and biochemical syndrome occurring when skeletal muscle cells erupt and result in release of creatine phosphokinase (CPK), lactate dehydrogenase (LDH) and myoglobin into the interstitial space and plasma.

Positive_regulation (result) of Localization (release) of myoglobin in skeletal muscle cells associated with disorders of creatine metabolism, syndrome and rhabdomyolysis

1) Confidence 0.33 Published 2007 Journal Hum Exp Toxicol Section Abstract Doc Link 17884958 Disease Relevance 1.16 Pain Relevance 0.05

To evaluate myocardial cell damage in relation to spontaneous and exercise-induced ischaemia, release of myoglobin, creatine kinase (CK) and its isoenzyme MB (CK-MB) into the serum was estimated in 10 patients with severe stable angina.

Positive_regulation (estimated) of Localization (release) of MB in myocardial cell associated with angina and cv unclassified under development

2) Confidence 0.04 Published 1992 Journal Eur. Heart J. Section Abstract Doc Link 1555615 Disease Relevance 0.44 Pain Relevance 0.17

General Comments

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