INT113736

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Context Info
Confidence 0.08
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.11
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mc4r) signal transducer activity (Mc4r)
Mc4r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Brush evoked pain 2 100.00 Very High Very High Very High
Thermal hyperalgesia 2 100.00 Very High Very High Very High
Spinal cord 5 95.80 Very High Very High Very High
Eae 1 82.48 Quite High
Lasting pain 1 80.84 Quite High
Pain 1 61.48 Quite High
antagonist 2 61.12 Quite High
agonist 2 60.52 Quite High
Analgesic 1 56.16 Quite High
neuralgia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 5 100.00 Very High Very High Very High
Hyperalgesia 3 100.00 Very High Very High Very High
Nociception 3 98.48 Very High Very High Very High
Injury 1 82.48 Quite High
Pain 2 80.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the upregulation of POMC and MC4, in parallel with the presence of tactile allodynia and thermal hyperalgesia, further supports the idea of MC system involvement in nociception.
Negative_regulation (supports) of Positive_regulation (upregulation) of MC4 associated with nociception, brush evoked pain and thermal hyperalgesia
1) Confidence 0.08 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 14559360 Disease Relevance 1.11 Pain Relevance 0.93

General Comments

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