INT113743

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Context Info
Confidence 0.05
First Reported 2003
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Agrp) plasma membrane (Mc3r) signal transducer activity (Mc3r)
Anatomy Link Frequency
spinal cord 2
Mc3r (Rattus norvegicus)
Agrp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 5 99.40 Very High Very High Very High
Thermal hyperalgesia 2 96.36 Very High Very High Very High
Brush evoked pain 2 95.36 Very High Very High Very High
Eae 1 91.84 High High
Lasting pain 1 90.20 High High
Pain 1 70.84 Quite High
antagonist 2 70.48 Quite High
agonist 2 69.88 Quite High
Analgesic 1 65.52 Quite High
neuralgia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 5 99.70 Very High Very High Very High
Hyperalgesia 3 96.36 Very High Very High Very High
Injury 1 91.84 High High
Pain 2 90.20 High High
Nociception 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MC4 and POMC transcript were upregulated in the spinal cord of neuropathic rats, whereas MC3 and AgRP expression were unaffected.
MC3 Neg (unaffected) Regulation (unaffected) of Gene_expression (expression) of AgRP in spinal cord associated with neuropathic pain and spinal cord
1) Confidence 0.05 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 14559360 Disease Relevance 0.90 Pain Relevance 0.98

General Comments

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