INT113813

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Context Info
Confidence 0.60
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 4
Disease Relevance 1.19
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (REG1B) extracellular region (REG1B)
Anatomy Link Frequency
granulocytes 2
REG1B (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 12 97.12 Very High Very High Very High
anesthesia 2 89.48 High High
cINOD 2 69.80 Quite High
Neuropeptide 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Sepsis 2 99.12 Very High Very High Very High
Injury 12 94.20 High High
Pancreatitis 2 91.44 High High
Stress 2 90.04 High High
INFLAMMATION 2 69.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Colocalization of increased RegI with gastric epithelial areas showing increased proliferation also suggests that RegI may be an important mediator of the resolution of mucosal injury that is characteristic of gastric adaptation to aspirin.
Positive_regulation (increased) of RegI associated with aspirin and injury
1) Confidence 0.60 Published 2003 Journal Lab. Invest. Section Abstract Doc Link 14563943 Disease Relevance 0.34 Pain Relevance 0.27
A time course analysis of RegI expression during the onset and offset of adaptation showed that mucosal RegI increased during the development of adaptation, was maintained during subsequent aspirin dosing, and returned to baseline levels once dosing had ceased and adaptation was lost-indicative of a causal role in the adaptation process.
Positive_regulation (increased) of RegI associated with aspirin
2) Confidence 0.35 Published 2003 Journal Lab. Invest. Section Abstract Doc Link 14563943 Disease Relevance 0.28 Pain Relevance 0.28
Pancreatic stone protein is highly increased during posttraumatic sepsis and activates neutrophil granulocytes.
Positive_regulation (increased) of Pancreatic stone protein in granulocytes associated with sepsis
3) Confidence 0.25 Published 2009 Journal Crit. Care Med. Section Title Doc Link 19325491 Disease Relevance 0.28 Pain Relevance 0.09
Pancreatic stone protein is highly increased during posttraumatic sepsis and activates neutrophil granulocytes.
Positive_regulation (increased) of Pancreatic stone protein in granulocytes associated with sepsis
4) Confidence 0.18 Published 2009 Journal Crit. Care Med. Section Title Doc Link 19325491 Disease Relevance 0.28 Pain Relevance 0.09

General Comments

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