INT113861

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Context Info
Confidence 0.00
First Reported 2003
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1H4) signal transduction (NR1H4) lyase activity (CA3)
nucleus (NR1H4) cytoplasm (CA3)
Anatomy Link Frequency
CAR 1
CA3 (Homo sapiens)
NR1H4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 1 61.44 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of the activity of these variants indicates that both hCAR2 and hCAR3 lose the ability to heterodimerize with RXR and lack transactivation activity in cotransfection experiments where either full-length receptor or GAL4 DNA-binding domain/CAR ligand binding domain chimeras were utilized.
hCAR3 Neg (lack) Binding (heterodimerize) of RXR in CAR
1) Confidence 0.00 Published 2003 Journal Mol. Genet. Metab. Section Abstract Doc Link 14567971 Disease Relevance 0 Pain Relevance 0.06

General Comments

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