INT113891

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Context Info
Confidence 0.21
First Reported 2003
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 4.86
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gsr) mitochondrion (Gsr) oxidoreductase activity (Gsr)
cytoplasm (Gsr)
Anatomy Link Frequency
neutrophils 2
stroma 1
inflammatory monocytes 1
F4/80 1
Gsr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 109 98.72 Very High Very High Very High
cytokine 64 88.40 High High
chemokine 32 61.44 Quite High
imagery 58 50.00 Quite Low
Paracetamol 5 50.00 Quite Low
cva 2 30.96 Quite Low
corticosteroid 17 29.28 Quite Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neutropenia 5 99.44 Very High Very High Very High
INFLAMMATION 118 98.72 Very High Very High Very High
Acute Liver Failure 3 97.92 Very High Very High Very High
Mycobacterial Infection 290 97.60 Very High Very High Very High
Infection 353 96.68 Very High Very High Very High
Polyps 40 95.96 Very High Very High Very High
Sprains And Strains 83 95.64 Very High Very High Very High
Familial Adenomatous Polyposis 44 89.64 High High
Weight Loss 6 89.32 High High
Pulmonary Aspergillosis 1 84.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunofluorescence staining revealed overlap of both CD11b (AlexaFluor 488) and Gr1 (AlexaFluor 594) with ProSense-680 signal (Fig. 4a–e), in cells that were dispersed through out the polyp stroma.
Gr1 Binding (overlap) of in stroma associated with polyps
1) Confidence 0.21 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2488397 Disease Relevance 0.47 Pain Relevance 0
METHODS/RESULTS: Mangafodipir is endowed with superoxide dismutase, catalase, and glutathione reductase activities.
glutathione reductase Binding (endowed) of
2) Confidence 0.12 Published 2003 Journal J. Hepatol. Section Body Doc Link 14568259 Disease Relevance 0.10 Pain Relevance 0
Strikingly, we show the induction of mRNAs associated with Gr1+ cells, namely neutrophils and inflammatory monocytes, takes place on day 12 and coincides with cellular accumulation of Gr1+ cells in M.tuberculosis-infected lungs.
Gr1 Binding (associated) of in inflammatory monocytes associated with mycobacterial infection and inflammation
3) Confidence 0.08 Published 2011 Journal PLoS ONE Section Abstract Doc Link PMC3020951 Disease Relevance 1.21 Pain Relevance 0.17
Neutrophils were depleted by using the monoclonal antibody RB6-8C5, which binds the myeloid differentiation antigen Gr-1 and leads to neutropenia lasting for three to four days at the dose administered in our experiments [17].
Gr-1 Binding (binds) of in Neutrophils associated with neutropenia
4) Confidence 0.05 Published 2010 Journal BMC Microbiol Section Body Doc Link PMC2859869 Disease Relevance 1.48 Pain Relevance 0.03
We also gated specifically on cells expressing high levels of F4/80+ that were also CD11b+, Gr-1?
Gr-1 Binding (were) of in F4/80
5) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2731172 Disease Relevance 0.39 Pain Relevance 0.06
Strikingly, we show the induction of mRNAs associated with Gr1+ cells, namely neutrophils and inflammatory monocytes, takes place on day 12 and coincides with cellular accumulation of Gr1+ cells in M.tuberculosis-infected lungs.
Gr1 Binding (associated) of in neutrophils associated with mycobacterial infection and inflammation
6) Confidence 0.03 Published 2011 Journal PLoS ONE Section Abstract Doc Link PMC3020951 Disease Relevance 1.21 Pain Relevance 0.17

General Comments

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