INT1139

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Context Info
Confidence 0.65
First Reported 1979
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 35
Total Number 36
Disease Relevance 19.19
Pain Relevance 12.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
CII 4
puncture 2
lymph nodes 1
ASC 1
articular cartilage 1
IgG-2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
intrathecal 66 99.98 Very High Very High Very High
tail-flick 1 99.68 Very High Very High Very High
Inflammation 293 99.24 Very High Very High Very High
qutenza 29 99.20 Very High Very High Very High
Neuritis 11 99.10 Very High Very High Very High
Arthritis 810 99.04 Very High Very High Very High
Neuropeptide 11 99.04 Very High Very High Very High
Morphine 11 98.96 Very High Very High Very High
opiate 5 98.64 Very High Very High Very High
cytokine 154 97.20 Very High Very High Very High
Disease Link Frequency Relevance Heat
Immunization 66 99.76 Very High Very High Very High
Pressure And Volume Under Development 209 99.72 Very High Very High Very High
Lumbar Puncture Related Headaches 12 99.58 Very High Very High Very High
INFLAMMATION 298 99.24 Very High Very High Very High
Experimental Autoimmune Neuritis 10 99.10 Very High Very High Very High
Arthritis 827 99.04 Very High Very High Very High
Rheumatoid Arthritis 227 99.00 Very High Very High Very High
Infection 34 98.92 Very High Very High Very High
Disease 229 98.56 Very High Very High Very High
Inflammatory Bowel Disease 10 97.48 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
20, clone Tec3, rat IgG2a, Dako), and anti-OCT3/4 (1?
Gene_expression (clone) of IgG2a
1) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440803 Disease Relevance 0 Pain Relevance 0
200, clone RA3-6B2, rat IgG2a, BD Biosciences,), anti-rat CD45R (1?
Gene_expression (clone) of IgG2a
2) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440803 Disease Relevance 0 Pain Relevance 0
The cell surface expression of MHC class I molecules was analyzed using locus and haplotype-specific mAbs anti-H2Kb (clone CTKb, mouse IgG2a, phycoerythrin (PE)-conjugated, Caltag Laboratories, Hamburg, Germany), and anti-H2Db (clone CTDb, mouse IgG2a, PE-conjugated, Caltag).
Spec (analyzed) Gene_expression (expression) of IgG2a
3) Confidence 0.58 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440803 Disease Relevance 0 Pain Relevance 0
Susceptibility to EAN in a rat F2 population segregated with high levels of anti-PNM IgG, as well as IgG2b and IgG2c isotype levels, which support that disease genes regulate preferential Th1/Th2 differentiation.
Gene_expression (levels) of IgG2c associated with disease and neuritis
4) Confidence 0.43 Published 2001 Journal J. Neuroimmunol. Section Abstract Doc Link 11585618 Disease Relevance 1.26 Pain Relevance 0.63
Susceptibility to EAN in a rat F2 population segregated with high levels of anti-PNM IgG, as well as IgG2b and IgG2c isotype levels, which support that disease genes regulate preferential Th1/Th2 differentiation.
Gene_expression (levels) of IgG2b associated with disease and neuritis
5) Confidence 0.43 Published 2001 Journal J. Neuroimmunol. Section Abstract Doc Link 11585618 Disease Relevance 1.26 Pain Relevance 0.63
IgG from control serum failed to produce this effect.
Neg (failed) Gene_expression (produce) of IgG
6) Confidence 0.36 Published 1991 Journal Neurosci. Lett. Section Abstract Doc Link 1787914 Disease Relevance 0.18 Pain Relevance 1.41
To determine the effect of T-614 on immunoglobulin subclasses, the total serum levels of IgM, IgG1, IgG2a, and IgG2b subclasses were quantified.
Gene_expression (levels) of IgG2b
7) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.52 Pain Relevance 0.28
Anti-CII antibody levels in sera from rats treated with combination therapy were markly decreased, as were levels of IgG1, IgG2a, IgG2b and IgM.
Gene_expression (levels) of IgG1 in CII
8) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.53 Pain Relevance 0.25
To determine the effect of T-614 on immunoglobulin subclasses, the total serum levels of IgM, IgG1, IgG2a, and IgG2b subclasses were quantified.
Gene_expression (levels) of IgG1
9) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.51 Pain Relevance 0.28
Anti-CII antibody levels in sera from rats treated with combination therapy were markly decreased, as were levels of IgG1, IgG2a, IgG2b and IgM.
Gene_expression (levels) of IgG2a in CII
10) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.53 Pain Relevance 0.25
To determine the effect of T-614 on immunoglobulin subclasses, the total serum levels of IgM, IgG1, IgG2a, and IgG2b subclasses were quantified.
Gene_expression (levels) of IgG2a
11) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.52 Pain Relevance 0.28
Anti-CII antibody levels in sera from rats treated with combination therapy were markly decreased, as were levels of IgG1, IgG2a, IgG2b and IgM.
Gene_expression (levels) of IgG2b in CII
12) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.54 Pain Relevance 0.25
The levels of IgA, IgE and IgG in bronchial lavage were also affected by capsaicin treatment; however, the results were heterogeneous.
Gene_expression (levels) of IgG associated with qutenza
13) Confidence 0.07 Published 1991 Journal Allergy Section Abstract Doc Link 1654749 Disease Relevance 0 Pain Relevance 0.83
The levels of IgA, IgE and IgG antibodies as well as immunoglobulins were measured in serum and supernatants from cultured lymph node cells, spleen cells and peripheral blood lymphocytes.
Gene_expression (levels) of IgG in lymphocytes
14) Confidence 0.07 Published 1991 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 2026471 Disease Relevance 0.23 Pain Relevance 0.63
One of the most striking effects by capsaicin treatment was the reduction of IgA and IgG synthesis in cultured lymphoid cells from aerosol immunized animals treated with capsaicin after immunization.
Gene_expression (synthesis) of IgG associated with qutenza and immunization
15) Confidence 0.07 Published 1991 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 2026471 Disease Relevance 0.27 Pain Relevance 0.84
We have utilized kaolin, zymosan, anti-rat IgG (anti-IgG) and the Reversed Passive Arthus (RPA) reaction to produce these oedema models.
Gene_expression (produce) of IgG associated with pressure and volume under development
16) Confidence 0.06 Published 1979 Journal Agents Actions Section Abstract Doc Link 157060 Disease Relevance 0.63 Pain Relevance 0.49
We have utilized kaolin, zymosan, anti-rat IgG (anti-IgG) and the Reversed Passive Arthus (RPA) reaction to produce these oedema models.
Gene_expression (produce) of IgG associated with pressure and volume under development
17) Confidence 0.06 Published 1979 Journal Agents Actions Section Abstract Doc Link 157060 Disease Relevance 0.63 Pain Relevance 0.49
No NR2B specific IgG was detected in sera from PBS or KLH group.
Gene_expression (detected) of IgG
18) Confidence 0.06 Published 2007 Journal Chin. Med. J. Section Body Doc Link 17517177 Disease Relevance 0.12 Pain Relevance 0
The operant data obtained from the sustained attention task showed that both 192 IgG Saporin lesions of the NbM and ibotenate lesions of the PPTg produce impairments on this test of sustained attention.
Gene_expression (lesions) of IgG Saporin
19) Confidence 0.05 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2257968 Disease Relevance 0 Pain Relevance 0
These were 192 IgG saporin lesion of the NbM (N = 9), ibotenate lesion of the PPTg (N = 15), and controls.
Gene_expression (lesion) of IgG saporin
20) Confidence 0.05 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2257968 Disease Relevance 0 Pain Relevance 0.05

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