INT113916

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Context Info
Confidence 0.60
First Reported 2003
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 1.88
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (C2)
Anatomy Link Frequency
blood 1
whisker 1
vertebra 1
C2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 12 98.24 Very High Very High Very High
Sciatica 4 92.80 High High
imagery 142 75.44 Quite High
nMDA receptor 42 62.16 Quite High
metalloproteinase 17 50.00 Quite Low
Spinal cord 20 46.40 Quite Low
anesthesia 16 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
Somatosensory cortex 10 5.00 Very Low Very Low Very Low
addiction 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dislocations 1 100.00 Very High Very High Very High
Disease 36 99.26 Very High Very High Very High
Neck Pain 4 98.24 Very High Very High Very High
Nerve Root Compression 4 92.80 High High
Cardiovascular Disease 43 90.32 High High
Increased Venous Pressure Under Development 15 88.92 High High
Injury 41 86.40 High High
Obesity 3 7.20 Low Low
Stroke 44 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patient presented with neck pain without any neurological deficits and radiology revealed a mobile, partially reducible dislocation of the C2 over C3 vertebra.
Spec (partially) Localization (dislocation) of C2 in vertebra associated with pain, neck pain and dislocations
1) Confidence 0.60 Published 2003 Journal Neurol India Section Abstract Doc Link 14571017 Disease Relevance 0.20 Pain Relevance 0.10
To determine if blood could be flowing through these collaterals to re-establish blood flow to MCA territory, we imaged the ipsi-ischemic C2 representation in additional +0 h rats (+0 h Distal, n?
Localization (representation) of C2 in blood
2) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890583 Disease Relevance 0 Pain Relevance 0.04
In +1 h animals, the area and the peak amplitude of C2 whisker representation were also larger than baseline levels at 24 hours post occlusion, though only the increase in area (rather than amplitude as seen in +0 h animals) reached significance (F1,18?
Localization (representation) of C2 in whisker
3) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890583 Disease Relevance 0.13 Pain Relevance 0.06
The apposition index was calculated as ratio of yellow puncta and total synaptophysin specific (red and yellow) puncta or as colocalization index of C2 and S2-imunoreactivities as ratio of yellow puncta and total S2-specific puncta.
Localization (colocalization) of C2
4) Confidence 0.08 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2443283 Disease Relevance 0 Pain Relevance 0.03
Consequently, a remarkable increase in disease duration with disease severity was observed in our study, ranging from 20.1 years for C2, via 23.4 years and 25.3 years for C3 and C4, respectively, to 29.8 years for C5&C6.
Localization (ranging) of C2 associated with disease
5) Confidence 0.06 Published 2010 Journal Hum Genet Section Body Doc Link PMC2871097 Disease Relevance 1.29 Pain Relevance 0
Therefore, for anatomic and biomechanical reasons, pedicle screws are preferred at C2 and perhaps at C7.
Localization (preferred) of C2
6) Confidence 0.05 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628078 Disease Relevance 0.26 Pain Relevance 0.09

General Comments

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