INT113949

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Context Info
Confidence 0.44
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FLNA) extracellular region (FLNA) plasma membrane (FLNA)
nucleus (FLNA) transcription factor binding (FLNA) cytoplasm (FLNA)
FLNA (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 1 97.68 Very High Very High Very High
mu opioid receptor 12 93.20 High High
Opioid 1 56.72 Quite High
agonist 2 49.76 Quite Low
Enkephalin 1 25.00 Low Low
imagery 4 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 2 98.60 Very High Very High Very High
Cardiovascular Disease 20 82.56 Quite High
Increased Venous Pressure Under Development 2 22.80 Low Low
Body Weight 3 17.28 Low Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Hyperhomocysteinemia 3 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Diarrhoea 1 5.00 Very Low Very Low Very Low
Htlv Types I And Ii 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, vitamin C improved FMD in homocystinuric patients, but it did not in control participants [30].
Positive_regulation (improved) of Gene_expression (improved) of FMD
1) Confidence 0.44 Published 2006 Journal PLoS Clinical Trials Section Body Doc Link PMC1488894 Disease Relevance 0.16 Pain Relevance 0
To investigate the role of filamin A in opioid receptor function and regulation, we used the melanoma cell line M2, which does not express filamin A, and its subclone A7, transfected with human filamin A cDNA.
Positive_regulation (transfected) of Gene_expression (transfected) of filamin associated with opioid receptor and skin cancer
2) Confidence 0.15 Published 2003 Journal Mol. Pharmacol. Section Abstract Doc Link 14573758 Disease Relevance 0.18 Pain Relevance 0.39

General Comments

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