INT114013

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Context Info
Confidence 0.47
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 3.51
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (ATP1A2) plasma membrane (ATP1A2) locomotion (ATP1A2)
transmembrane transport (ATP1A2) cytoplasm (ATP1A2)
ATP1A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 1 100.00 Very High Very High Very High
Migraine 15 98.96 Very High Very High Very High
Pain 1 90.80 High High
Central nervous system 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Migraine With Aura 9 99.56 Very High Very High Very High
Headache 6 98.96 Very High Very High Very High
Epilepsy 5 98.44 Very High Very High Very High
Toxicity 6 95.92 Very High Very High Very High
Paresis 2 94.12 High High
Neuropathic Pain 1 89.52 High High
Congenital Anomalies 4 89.08 High High
Pressure And Volume Under Development 1 88.48 High High
Alopecia 1 88.32 High High
Coma 1 87.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures.
ATP1A2 Binding (associated) of associated with epilepsy and migraine
1) Confidence 0.47 Published 2008 Journal J. Neurol. Sci. Section Title Doc Link 18644608 Disease Relevance 1.68 Pain Relevance 0.76
Additional effects include inhibition of sodium-potassium-adenosine triphosphatase and binding to sulfhydryl groups.
sodium-potassium-adenosine triphosphatase Binding (binding) of associated with adenocard
2) Confidence 0.37 Published 2003 Journal Toxicol Rev Section Abstract Doc Link 14579545 Disease Relevance 1.01 Pain Relevance 0.14
Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine.
ATP1A2 Binding (associated) of associated with migraine with aura and migraine
3) Confidence 0.35 Published 2006 Journal Eur. J. Hum. Genet. Section Title Doc Link 16538223 Disease Relevance 0.82 Pain Relevance 0.56

General Comments

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