INT114031

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Context Info
Confidence 0.41
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 6.31
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ORM1) extracellular space (ORM1) extracellular region (ORM1)
Anatomy Link Frequency
brain 1
ORM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 15 93.88 High High
methadone 11 93.88 High High
cINOD 5 91.00 High High
Central nervous system 16 89.64 High High
Inflammation 34 85.44 High High
antagonist 2 72.48 Quite High
Fibrositis 24 5.00 Very Low Very Low Very Low
Pain 12 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
spastic colon 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Takayasu Arteritis 250 99.98 Very High Very High Very High
Autoimmune Disease 160 98.84 Very High Very High Very High
Brain Injury 3 97.80 Very High Very High Very High
Syndrome 99 97.36 Very High Very High Very High
Microscopic Polyangiitis 30 95.56 Very High Very High Very High
Malignant Neoplastic Disease 5 94.28 High High
Rheumatoid Arthritis 30 93.88 High High
Vasculitis 20 93.48 High High
INFLAMMATION 39 90.76 High High
Chronic Fatigue Syndrome 184 80.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Enantioselective separations were achieved on a liquid chromatographic chiral stationary phase (CSP) based upon immobilized alpha(1)-acid glycoprotein (AGP) using a mobile phase composed of acetonitrile: ammonium acetate buffer (10mM, pH 7.0) in a ratio of 18:82 (v/v), a flow rate of 0.9 ml/min and a temperature of 25 degrees C.
Gene_expression (based) of acid glycoprotein
1) Confidence 0.41 Published 2003 Journal J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. Section Abstract Doc Link 14581075 Disease Relevance 0 Pain Relevance 0.71
Both ORM2 and ORM1 are acute phase reactants that are synthesized in the liver, but may also be synthesized at sites of brain injury or astroglial cell activation [59].
Gene_expression (synthesized) of ORM1 in brain associated with brain injury
2) Confidence 0.37 Published 2005 Journal BMC Neurol Section Body Doc Link PMC1326206 Disease Relevance 0.66 Pain Relevance 0.23
These probes were termed aGp (Supplementary Table S2: aGp #1–216), and the Genopal™ array performed with these probes was called an aGp array.
Gene_expression (termed) of aGp
3) Confidence 0.08 Published 2010 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2993541 Disease Relevance 1.06 Pain Relevance 0.08
Figure 4.Expression profiling with the aGp array.
Gene_expression (4.Expression) of aGp
4) Confidence 0.08 Published 2010 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2993541 Disease Relevance 2.12 Pain Relevance 0.03
Data analysis of aGp array
Gene_expression (array) of aGp
5) Confidence 0.08 Published 2010 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2993541 Disease Relevance 0.34 Pain Relevance 0
In addition, the correlation coefficients of DEFA3 for the averaged signal intensities of the aGp array and Agilent's microarray against qPCR normalized to GAPDH (0.93 and 0.96) are significantly higher than those of IL-4 (?
Gene_expression (array) of aGp
6) Confidence 0.08 Published 2010 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2993541 Disease Relevance 0.20 Pain Relevance 0
Additionally, the TA aGp arrays were also tested with other autoimmune diseases such as Behçet's syndrome (BD), Churg–Strauss syndrome (CSS), microscopic polyangiitis (MPA), malignant RA (MRA), polyarteritis nodosa (PN) and Wegener's granulomatosis (WG), as well as with normal volunteers (Nor) as comparable target samples (Supplementary Fig.
Gene_expression (arrays) of aGp associated with takayasu arteritis, malignant neoplastic disease, autoimmune disease, syndrome, rheumatoid arthritis, vasculitis and microscopic polyangiitis
7) Confidence 0.08 Published 2010 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2993541 Disease Relevance 1.93 Pain Relevance 0.14

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