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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CREM, JUN) DNA binding (CREM, JUN) cytosol (JUN)
nucleoplasm (JUN) cell differentiation (CREM) nuclear chromosome (JUN)
CREM (Homo sapiens)
JUN (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 88.80 High High
Pain 1 82.12 Quite High
antagonist 1 79.92 Quite High
COX-2 inhibitor 1 55.92 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 90.96 High High
Pain 1 82.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Electrophoretic mobility shift assays and supershift experiments revealed a marked increase in the binding of activator protein-1 (AP-1)(c-Jun/c-Fos) to the cyclic AMP response element of the COX-2 promoter.
Positive_regulation (increase) of AMP response element Binding (binding) of activator protein-1
1) Confidence 0.04 Published 2003 Journal Clin. Cancer Res. Section Abstract Doc Link 14581379 Disease Relevance 0.17 Pain Relevance 0.19

General Comments

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