INT114273

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Context Info
Confidence 0.24
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.81
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nts)
Anatomy Link Frequency
margin 2
lateral ventricle 2
Nts (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 41 100.00 Very High Very High Very High
Enkephalin 2 98.62 Very High Very High Very High
Dopamine 3 94.56 High High
Neuropeptide 4 94.48 High High
Locus ceruleus 1 94.04 High High
Cholecystokinin 96 93.12 High High
antagonist 23 93.04 High High
analgesia 2 86.00 High High
agonist 6 83.28 Quite High
Dynorphin 1 75.84 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 3 99.40 Very High Very High Very High
Catalepsy 2 98.08 Very High Very High Very High
Anxiety Disorder 1 84.68 Quite High
Body Weight 2 70.80 Quite High
Ganglion Cysts 1 70.80 Quite High
Aids-related Complex 5 65.72 Quite High
Depression 18 5.00 Very Low Very Low Very Low
Convulsion 6 5.00 Very Low Very Low Very Low
Hypoxia 5 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, injection of the CART peptide either into the third, fourth, or the lateral ventricle suppressed food intake [11,12,14,19,20] and stimulated expression of c-Fos in NTS, the parabranchial nucleus, PVN and DMH [21,22].
Negative_regulation (suppressed) of Gene_expression (expression) of NTS in lateral ventricle associated with medulla
1) Confidence 0.24 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0.34 Pain Relevance 0.88
The final cut then progressed along the ventromedial margin of SP5 to the ventrolateral surface of the slice, thereby removing the contralateral preBötC, NTS, SP5, XIIn, XII tract, and the IO (c.f.
Negative_regulation (removing) of Gene_expression (tract) of NTS in margin
2) Confidence 0.12 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2567986 Disease Relevance 0 Pain Relevance 0
Haloperidol-induced increase of striatal enkephalin mRNA is totally abolished in NGFI-B KO mice whereas the increase of neurotensin mRNA expression is reduced by 50%.
Negative_regulation (reduced) of Gene_expression (expression) of neurotensin mRNA associated with targeted disruption and enkephalin
3) Confidence 0.06 Published 2004 Journal Neuropsychopharmacology Section Abstract Doc Link 14603264 Disease Relevance 0.47 Pain Relevance 0.56

General Comments

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