INT114293

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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Stat6) nucleus (Stat6) DNA binding (Stat6)
cytoplasm (Stat6) signal transducer activity (Stat6)
Anatomy Link Frequency
lung 1
Stat6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 58 96.48 Very High Very High Very High
Inflammation 16 92.80 High High
Inflammatory response 3 82.40 Quite High
cINOD 1 71.80 Quite High
Central nervous system 7 54.04 Quite High
Potency 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 92.80 High High
Rhinitis 1 92.28 High High
Asthma 4 81.12 Quite High
Airway Obstruction 1 63.44 Quite High
Infection 197 62.00 Quite High
Disease 1 61.72 Quite High
Cold Sores 214 52.72 Quite High
Repression 1 47.36 Quite Low
Coronavirus Infection 1 31.16 Quite Low
Severe Acute Respiratory Syndrome 1 30.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, binding of signal transducer and activator of transcription 6 (STAT6) and nuclear factor kappa B (NF-kappa B) oligonucleotides to lung nuclear proteins was significantly reduced in mice treated with inhaled APC.
STAT6 Binding (binding) of in lung
1) Confidence 0.44 Published 2004 Journal Blood Section Abstract Doc Link 14604971 Disease Relevance 0.91 Pain Relevance 0.48
The human promoter region of IRF-2 contains a SBE, and the induction of IRF-2 could thus potentially be mediated by STAT6 binding to this element [442].
STAT6 Binding (binding) of
2) Confidence 0.17 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 0.38 Pain Relevance 0.03

General Comments

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