INT1143

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Context Info
Confidence 0.67
First Reported 1979
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 5.38
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (OTOR)
Anatomy Link Frequency
plasma 1
shoulder 1
endothelial cells 1
lumen 1
fibrocyte 1
OTOR (Homo sapiens)
Pain Link Frequency Relevance Heat
shoulder pain 3 99.90 Very High Very High Very High
Inflammatory marker 2 98.84 Very High Very High Very High
Angina 2 96.68 Very High Very High Very High
abdominal pain 2 93.44 High High
Serotonin 1 91.60 High High
cINOD 1 86.16 High High
backache 1 84.36 Quite High
aspirin 5 77.28 Quite High
cytokine 7 55.88 Quite High
Inflammation 15 55.52 Quite High
Disease Link Frequency Relevance Heat
Shoulder Pain 3 99.90 Very High Very High Very High
Congenital Anomalies 1 99.76 Very High Very High Very High
Colitis 2 98.96 Very High Very High Very High
INFLAMMATION 19 98.84 Very High Very High Very High
Syndrome 2 98.76 Very High Very High Very High
Increased Venous Pressure Under Development 2 98.58 Very High Very High Very High
Myocardial Infarction 3 98.16 Very High Very High Very High
Recurrence 2 97.88 Very High Very High Very High
Cancer 5 97.16 Very High Very High Very High
Cv General 3 Under Development 2 96.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The levels of plasma plasminogen, fibrinogen and FDP were also significantly changed in these patients.
Positive_regulation (changed) of FDP in plasma
1) Confidence 0.67 Published 1989 Journal Chin. Med. J. Section Abstract Doc Link 2517077 Disease Relevance 0.80 Pain Relevance 0.19
FDP and fibrinogen levels were elevated, and abnormalities of the coagulation and fibrinolytic factors were found at the onset of the symptoms.
Positive_regulation (elevated) of FDP associated with congenital anomalies
2) Confidence 0.67 Published 1995 Journal Nippon Jinzo Gakkai Shi Section Abstract Doc Link 7666601 Disease Relevance 1.07 Pain Relevance 0.09
Marked elevation of fibrinogen, thrombin-antithrombin III complex (TAT), plasmin-alpha(2) plasmin inhibitor complex (PIC), fibrin degradation products (FDP), and D-Dimer indicated the activation of both coagulation and fibrinolysis in the false lumen.
Positive_regulation (elevation) of FDP in lumen
3) Confidence 0.67 Published 1996 Journal Kyobu Geka Section Abstract Doc Link 8913071 Disease Relevance 0.34 Pain Relevance 0.08
However, plasma TIA became positive again one month later, in association with reappearance of shoulder pain and elevation of FDP and fibrinogen levels, which were considered due to recurrence of the tumor, 30 Gy of Liniack together with thermotherapy was again given.
Positive_regulation (elevation) of FDP in shoulder associated with cancer, shoulder pain and recurrence
4) Confidence 0.64 Published 1992 Journal Nihon Kyobu Shikkan Gakkai Zasshi Section Abstract Doc Link 1447849 Disease Relevance 0.78 Pain Relevance 0.27
The patient was referred to our hospital, and suspected to have vasculitis syndrome since the abnormal laboratory findings included persistently increased levels of FDP-E/fibrin monomer as well as inflammatory markers, and the extraordinary high excretion of beta 2-microglobulin, which indicated abrupt and massive expression of HLA class I molecule on endothelial cells due to interferon-gammanemia.
Positive_regulation (increased) of FDP in endothelial cells associated with syndrome, inflammatory marker and increased venous pressure under development
5) Confidence 0.45 Published 2008 Journal Nihon Rinsho Meneki Gakkai Kaishi Section Abstract Doc Link 18974626 Disease Relevance 1.31 Pain Relevance 0.13
On activation of the fibrinolytic cascade, plasmin catalyzes fibrin to FDP, increasing FDP levels.
Positive_regulation (increasing) of FDP
6) Confidence 0.27 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2872884 Disease Relevance 0.36 Pain Relevance 0.06
Processes 2) and 3) are dependent upon the fibroblast, which is an activated fibrocyte.
Positive_regulation (activated) of fibrocyte in fibrocyte
7) Confidence 0.01 Published 1979 Journal Med. Biol. Section Abstract Doc Link 159985 Disease Relevance 0.72 Pain Relevance 0.17

General Comments

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