INT114340

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Context Info
Confidence 0.07
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.42
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (KNG1) extracellular region (KNG1) plasma membrane (KNG1)
KNG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 11 100.00 Very High Very High Very High
Glutamate receptor 1 91.40 High High
gABA 1 87.76 High High
cINOD 2 72.88 Quite High
Pain 7 70.80 Quite High
aspirin 4 68.56 Quite High
antagonist 5 30.64 Quite Low
headache 3 24.72 Low Low
Migraine 5 23.56 Low Low
Inflammation 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 1 93.44 High High
Cardiovascular Disease 7 90.40 High High
Increased Venous Pressure Under Development 17 85.20 High High
Bacterial Skin Infection 12 84.96 Quite High
Schizophrenia 4 76.36 Quite High
Weight Loss 42 73.80 Quite High
INFLAMMATION 7 72.48 Quite High
Infection 2 72.32 Quite High
Exanthema 2 70.36 Quite High
Fever 4 69.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
degradation of bradykinin and contribute to accumulation of
Positive_regulation (contribute) of Protein_catabolism (degradation) of bradykinin associated with bradykinin
1) Confidence 0.07 Published 2004 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC555773 Disease Relevance 0.33 Pain Relevance 0.32
Degradation of high-molecular-weight kininogen and upregulation of the bradykinin-1 receptor in inflamed tissues indicated activation of the contact system in 11 patients.
Positive_regulation (activation) of Protein_catabolism (Degradation) of high-molecular-weight kininogen associated with bradykinin
2) Confidence 0.06 Published 2010 Journal J. Invest. Dermatol. Section Abstract Doc Link 20107486 Disease Relevance 0.65 Pain Relevance 0.19
Degradation of high-molecular-weight kininogen and upregulation of the bradykinin-1 receptor in inflamed tissues indicated activation of the contact system in 11 patients.
Positive_regulation (upregulation) of Protein_catabolism (Degradation) of high-molecular-weight kininogen associated with bradykinin
3) Confidence 0.06 Published 2010 Journal J. Invest. Dermatol. Section Abstract Doc Link 20107486 Disease Relevance 0.65 Pain Relevance 0.18
The goal of the remaining 6 month will be to facilitate the continued evolution of behavior changes achieved to date and to promote long-term weight stability.
Positive_regulation (promote) of Protein_catabolism (stability) of weight
4) Confidence 0.02 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2860346 Disease Relevance 0.28 Pain Relevance 0
ACE transforms angiotensin I (Ang I) to angiotensin II (Ang II), and also promotes the degradation of bradykinin into inactive metabolites.
Positive_regulation (promotes) of Protein_catabolism (degradation) of bradykinin associated with bradykinin
5) Confidence 0.02 Published 2003 Journal J Renin Angiotensin Aldosterone Syst Section Abstract Doc Link 14608518 Disease Relevance 0.51 Pain Relevance 0.23

General Comments

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