INT114409

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Context Info
Confidence 0.35
First Reported 2003
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 1.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Lyz2) extracellular region (Lyz2) cytoplasm (Lyz2)
Lyz2 (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 6 97.92 Very High Very High Very High
mu opioid receptor 1 96.88 Very High Very High Very High
Antinociceptive 6 95.36 Very High Very High Very High
MU agonist 1 92.88 High High
agonist 1 89.12 High High
Intracerebroventricular 2 88.56 High High
Analgesic 2 83.84 Quite High
tail-flick 1 83.52 Quite High
intrathecal 1 82.16 Quite High
antinociception 4 73.04 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cyclic analogs of the opioid peptides endomorphin-2 and morphiceptin of the type Tyr-X-Phe-Phe-Y-NH2 and Tyr-X-Phe-D-Pro-Y-NH2 (X = Lys or Asp and Y = Lys or Asp), respectively, were synthesized in order to test their structure-activity relationships.
Gene_expression (synthesized) of Lys associated with opioid
1) Confidence 0.35 Published 2005 Journal Biochem. Pharmacol. Section Abstract Doc Link 16288997 Disease Relevance 0 Pain Relevance 0.56
Cyclic analogs of the opioid peptides endomorphin-2 and morphiceptin of the type Tyr-X-Phe-Phe-Y-NH2 and Tyr-X-Phe-D-Pro-Y-NH2 (X = Lys or Asp and Y = Lys or Asp), respectively, were synthesized in order to test their structure-activity relationships.
Gene_expression (synthesized) of Lys associated with opioid
2) Confidence 0.35 Published 2005 Journal Biochem. Pharmacol. Section Abstract Doc Link 16288997 Disease Relevance 0 Pain Relevance 0.56
Fluorescent analogues of [Dmt1] DALDA containing either beta-dansyl-L-alpha,beta-diaminopropionic acid [Dap(dns)] or beta-anthraniloyl-L-alpha,beta-diaminopropionic acid [Dap(atn)] in place of Lys4 were synthesized.
Gene_expression (synthesized) of Lys4
3) Confidence 0.01 Published 2003 Journal Peptides Section Abstract Doc Link 14612191 Disease Relevance 0 Pain Relevance 0.52

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