INT114446

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.59
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CAMK2D) nucleoplasm (CAMK2D) plasma membrane (CAMK2D)
nucleus (CAMK2D) cytoplasm (CAMK2D)
Anatomy Link Frequency
taste bud 1
L-2 1
CAMK2D (Homo sapiens)
Pain Link Frequency Relevance Heat
nMDA receptor 2 99.20 Very High Very High Very High
sodium channel 23 98.76 Very High Very High Very High
ASIC 25 96.68 Very High Very High Very High
tetrodotoxin 1 95.58 Very High Very High Very High
cerebral cortex 1 75.00 Quite High
Inflammation 2 26.36 Quite Low
Endep 4 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 5 85.88 High High
Ageusia 16 71.96 Quite High
Myasthenia Gravis 1 50.64 Quite High
Lower Respiratory Tract Infection 2 46.04 Quite Low
Taste Disorders 1 40.28 Quite Low
Apoptosis 1 33.44 Quite Low
Viral Infection 1 28.16 Quite Low
INFLAMMATION 2 26.36 Quite Low
Injury 1 17.24 Low Low
Critical Illness 1 8.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 2002 we reported that the delta subunit is preferentially expressed and abundant in the human taste bud [36].
Gene_expression (expressed) of delta subunit in taste bud
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2754526 Disease Relevance 0.23 Pain Relevance 0.14
Prior exposure to tetrodotoxin prevented the changes in CaMKII-alpha and CaMKII-delta mRNA regulation and this was mimicked by D-L-2-amino-5-phosphonovaleric acid, but not by 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline, suggesting that CaMKII-alpha and CaMKII-delta mRNA expression is regulated in an N-methyl-D-aspartate receptor-dependent manner.
Gene_expression (expression) of CaMKII-delta mRNA in L-2 associated with tetrodotoxin and nmda receptor
2) Confidence 0.01 Published 2003 Journal Neuroscience Section Abstract Doc Link 14614906 Disease Relevance 0.36 Pain Relevance 0.22

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox