INT114453

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.72
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Camk1) signal transduction (Camk1) nucleocytoplasmic transport (Camk1)
nucleus (Camk1) cell cycle (Camk1) cytoplasm (Camk1)
Anatomy Link Frequency
L-2 1
Camk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 99.48 Very High Very High Very High
nMDA receptor 4 94.60 High High
cerebral cortex 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Convulsion 10 93.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prior exposure to tetrodotoxin prevented the changes in CaMKII-alpha and CaMKII-delta mRNA regulation and this was mimicked by D-L-2-amino-5-phosphonovaleric acid, but not by 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline, suggesting that CaMKII-alpha and CaMKII-delta mRNA expression is regulated in an N-methyl-D-aspartate receptor-dependent manner.
Regulation (regulation) of CaMKII-alpha in L-2 associated with tetrodotoxin and nmda receptor
1) Confidence 0.01 Published 2003 Journal Neuroscience Section Abstract Doc Link 14614906 Disease Relevance 0.37 Pain Relevance 0.22
Blocking transcription with actinomycin-D prevented activity-dependent changes in CaMKII-alpha and CaMKII-delta mRNA, but produced opposite effects on basal transcription, resulting in more stabilized CaMKII-alpha mRNA and less stabilized CaMKII-delta mRNA.
Regulation (changes) of CaMKII-alpha
2) Confidence 0.01 Published 2003 Journal Neuroscience Section Abstract Doc Link 14614906 Disease Relevance 0.34 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox