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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Bap1) nucleolus (Bap1) nucleus (Bap1)
intracellular (Bap1) cytoplasm (Bap1)
Anatomy Link Frequency
microglial cells 2
Bap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 1 99.32 Very High Very High Very High
cINOD 3 95.48 Very High Very High Very High
aspirin 1 94.36 High High
Inflammation 1 75.00 Quite High
Inflammatory response 1 74.64 Quite High
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 4 97.44 Very High Very High Very High
INFLAMMATION 3 94.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Marked reduction of dopamine transporter-positive signals and accumulation of microglial cells in the striatum after METH injections (4 mg/kg x4, i.p. with 2 h-interval) were significantly and dose-dependently attenuated by four injections of ketoprofen (2 or 5 mg/kg x4, s.c.) given 30 min prior to each METH injection, but not by either a low or high dose of aspirin.
Negative_regulation (attenuated) of Positive_regulation (accumulation) of x4 in microglial cells associated with aspirin and dopamine
1) Confidence 0.36 Published 2003 Journal Neurosci. Lett. Section Abstract Doc Link 14615038 Disease Relevance 0.50 Pain Relevance 0.42

General Comments

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