INT114536

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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1) nucleus (Creb1) DNA binding (Creb1)
transcription factor binding (Creb1)
Anatomy Link Frequency
NAc 2
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 5 97.08 Very High Very High Very High
Ventral tegmentum 5 96.92 Very High Very High Very High
Morphine 1 94.48 High High
cocaine 1 93.72 High High
Dopamine 2 81.88 Quite High
addiction 2 74.56 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consequently, the 90% reduction of CREB in CREBalphaDelta mutant mice differentially affects CREB phosphorylation and induction of downstream targets of CREB in the NAc and VTA.
Regulation (affects) of Negative_regulation (reduction) of CREB in NAc associated with ventral tegmentum and nucleus accumbens
1) Confidence 0.45 Published 2003 Journal J. Neurochem. Section Abstract Doc Link 14622103 Disease Relevance 0 Pain Relevance 0.72

General Comments

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