INT11458

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Context Info
Confidence 0.39
First Reported 1989
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 2.51
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Tap2) endoplasmic reticulum (Tap2) ATPase activity (Tap2)
plasma membrane (Tap2) nucleus (Tap2) protein complex assembly (Tap2)
Anatomy Link Frequency
spleens 2
Tap2 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 1 97.08 Very High Very High Very High
Pain 1 95.32 Very High Very High Very High
alcohol 1 94.80 High High
Angina 2 91.04 High High
Neuropeptide 2 89.36 High High
antagonist 1 84.80 Quite High
spinal inflammation 1 75.00 Quite High
Potency 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurosis 8 99.36 Very High Very High Very High
Infection 57 99.04 Very High Very High Very High
Sleep Disorders 6 98.96 Very High Very High Very High
Syndrome 1 97.88 Very High Very High Very High
Arthritis 1 97.08 Very High Very High Very High
Targeted Disruption 1 96.32 Very High Very High Very High
Pain 1 95.32 Very High Very High Very High
Anxiety Disorder 1 94.44 High High
Coronary Artery Disease 1 93.36 High High
Angina 1 91.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we show that NPY increases sedation induced by different types of anaesthetics through interactions with the Y1 receptor.
Y1 Binding (interactions) of associated with sleep disorders
1) Confidence 0.39 Published 2001 Journal Eur. J. Neurosci. Section Abstract Doc Link 11454027 Disease Relevance 0.77 Pain Relevance 0.27
This would imply that when mouse TAP1 or TAP2 associates with its human TAP counterpart, they play a dominant role in selecting the peptides for transport.
TAP2 Binding (associates) of
2) Confidence 0.20 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0 Pain Relevance 0
RT-PCR was used to detect human TAP1 and TAP2, and mouse TAP1 and TAP2, in spleens 24 h after infection.
TAP2 Binding (detect) of in spleens associated with infection
3) Confidence 0.20 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0.25 Pain Relevance 0
RT-PCR was used to detect human TAP1 and TAP2, and mouse TAP1 and TAP2, in spleens 24 h after infection.
TAP2 Binding (detect) of in spleens associated with infection
4) Confidence 0.20 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0.25 Pain Relevance 0
Clinical data may now allow early recognition of JAS through the identification of children with the SEA syndrome or chronic arthritis associated with the HLA-B27.
JAS Binding (recognition) of associated with syndrome and arthritis
5) Confidence 0.05 Published 1992 Journal Rheum. Dis. Clin. North Am. Section Abstract Doc Link 1561399 Disease Relevance 0.36 Pain Relevance 0.12
The present study examined associations of the SI, JAS, and FTAS with neuroticism and symptom reporting in two independent samples of undergraduate males.
JAS Spec (examined) Binding (associations) of associated with neurosis
6) Confidence 0.05 Published 1989 Journal J Behav Med Section Abstract Doc Link 2746639 Disease Relevance 0.89 Pain Relevance 0.18

General Comments

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