INT114592

Context Info Confidence 0.27 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.09 Pain Relevance 0.40

signal transduction (Il1rap) extracellular space (Il1b) aging (Il1b) extracellular region (Il1b) intracellular (Il1rap) protein binding, bridging (Il1rap)

Il1b (Rattus norvegicus) Il1rap (Rattus norvegicus)

Pain Link Frequency Relevance Heat substance P 12 98.60 spinal dorsal horn 1 92.80 Pain 2 91.32 antagonist 1 25.00

Disease Link Frequency Relevance Heat Pain 2 91.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Stimulation of IL-1 receptor by IL-1beta may induce the phosphorylation of tyrosine residues in many effector proteins through the activation of p60c-src kinase.

IL-1beta Positive_regulation (Stimulation) of IL-1 receptor

1) Confidence 0.27 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 14622206 Disease Relevance 0.09 Pain Relevance 0.40

General Comments

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