INT114599

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Il1rap) enzyme binding (Trib3) protein binding, bridging (Il1rap)
protein complex (Il1rap) signal transducer activity (Il1rap) signal transduction (Il1rap)
Anatomy Link Frequency
neurons 2
Il1rap (Rattus norvegicus)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 12 86.96 High High
spinal dorsal horn 1 71.72 Quite High
Pain 2 70.24 Quite High
antagonist 1 53.52 Quite High
Disease Link Frequency Relevance Heat
Pain 2 70.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment of DRG neurons in culture with herbimycin A, genistein or PP2, three structurally different nonreceptor tyrosine kinase inhibitors that act by different mechanisms, decreased the kinase activity of p60c-src induced by the activation of IL-1 receptor.
Positive_regulation (activation) of IL-1 receptor in neurons Positive_regulation (induced) of kinase
1) Confidence 0.03 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 14622206 Disease Relevance 0.07 Pain Relevance 0.43

General Comments

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